The Chicken Frizzle Feather Is Due to an Alpha-Keratin (KRT75) Mutation That Causes a Defective Rachis

July 2012 in “ PLoS Genetics ”

Chen Siang Ng, Ping Wu, John Foley, Anne Foley, Merry‐Lynn McDonald, Wen‐Tau Juan, Chih-Jen Huang, Yu-Ting Lai, Wen-Sui Lo, Chih-Feng Chen, Suzanne M. Leal, Huanmin Zhang, Randall B. Widelitz, Pragna I. Patel, Wen‐Hsiung Li, Cheng‐Ming Chuong

α-keratin KRT75 keratin dimerization autosomal incomplete dominant retroviral-mediated expression feather morphology

Studysummary This study identified a 69 bp deletion in the KRT75 gene as the cause of the frizzle feather trait in chickens, affecting feather curling.

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