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This review discusses the potential of secretome derived from stem cells for treating alopecia areata and reports no new clinical results; the authors suggest the need for further human trials.

This review discusses the potential of extracellular vesicles from various sources as promising candidates for hair growth stimulation but notes that clinical trials are needed to confirm their effectiveness and safety.

In this study, mesenchymal stem cell therapy improved erectile function in a rat model of diabetes-associated erectile dysfunction, and identified 15 hub genes potentially involved in the condition's development.

This review discusses the potential of mesenchymal stem cell therapies for treating various skin diseases, including vitiligo, alopecia, and epidermolysis bullosa, but reports no new results.

This study successfully cultured human fetal hair follicle-derived melanocytes, which showed high proliferative capabilities and unique morphological characteristics compared to adult-derived cells, potentially advancing hair disease research.

In this study, KC-AD-MSCs were found to increase COL7 deposition and anchoring fibril formation at the dermal-epidermal junction in a RDEB mouse model, suggesting potential for improving skin integrity in recessive dystrophic epidermolysis bullosa patients.

This study found that combining mesenchymal stromal cells from adipose tissue and hair follicles with soy protein and β-chitin scaffolds significantly reduced wound healing time and improved skin regeneration in vivo.

This review discusses how mesenchymal stromal cell-based therapy holds promise for treating age-related diseases, given its potential to target aging's pathological features, although significant challenges remain for its clinical application.

In this study, MSC-derived magnetic nanovesicles combined with a magnetic field increased skin retention and accelerated hair follicle growth in a mouse model of hair regeneration.

This review reports limited evidence suggesting that stem cell-based therapies, particularly using human-derived mesenchymal stem cells and exosomes, may be effective for skin rejuvenation, though results are uncertain due to methodological limitations and variability across studies.

This review found that while MSC and EV-based therapies could potentially improve skin and hair rejuvenation, their clinical efficacy is limited by inconsistent study designs and a lack of standardization.

This review discusses current advancements in mesenchymal stem cell-based therapies for skin repair and rejuvenation, focusing on therapeutic strategies, particularly highlighting the potential of neonatal and placenta-derived MSCs, and reports no new clinical results.

This review highlights the potential of stem cell-based therapies, including hair follicle, mesenchymal, and induced pluripotent stem cells, as promising future treatments for alopecia, noting their regenerative and immunomodulatory capabilities as well as ongoing studies evaluating their effectiveness in overcoming current therapy limitations.

In this study, researchers identified KRT6A as a potentially important gene in mesenchymal stem cell-derived treatments for alopecia areata, revealing its role as a diagnostic marker, predictor of disease severity, and a protective factor, with overexpression alleviating hair loss in experimental models.

This article reviews the use of biologics like platelet-rich plasma and mesenchymal stem cells in plastic surgery but highlights a lack of standardization in reporting platelet concentrations, which limits the systematic evaluation of their efficacy and application.

This study found that mesenchymal stem cells mainly promote skin regeneration and delay aging through paracrine activity, releasing growth factors and cytokines that protect against oxidative stress and stimulate healing.

In this case report, two young women with female pattern hair loss experienced significant hair regrowth without adverse effects after six months of treatment with bone-marrow-derived mesenchymal stem cells and their extracellular vesicles, suggesting potential for this approach when conventional treatments fail.

This review explores the potential of mesenchymal stem cells in skin regeneration and rejuvenation, highlighting their ability to modulate immune response and enhance extracellular matrix strength but does not provide new clinical evidence.

This review found that adipose-derived stem cells and stromal vascular fraction have robust clinical benefits in aesthetic surgery, particularly in facial rejuvenation, scar treatment, and volumetric restoration, with favorable safety profiles.

This study evaluated the effects of exosome therapy from hypoxia-treated mesenchymal stem cells on a fluconazole-induced alopecia model in rats and found that it significantly reduced TNF-α and increased VEGF levels, suggesting potential as a novel regenerative treatment for alopecia.

This review reports significant advancements in plastic surgery using stem cell therapies for aesthetic and reconstructive applications, including grafting and wound healing, though it underscores the need for continued research to address regulatory, ethical, and standardization issues.

This review highlights the lack of a comprehensive synthesis of stem cell therapy research by categorizing current studies according to medical specialty and stem cell type, while analyzing their advantages and limitations across various medical disciplines.

This review discusses recent advancements in hair loss treatments, including stem cell and hair follicle cell therapies, growth factors, extracellular vesicles, gene therapy, and tissue engineering, highlighting their potential in improving hair regeneration and follicle health.

The systematic review reported promising outcomes for stem cell-enriched treatments in aesthetic medicine, such as improved skin rejuvenation, hair restoration, and scar revision. However, challenges like protocol variability and regulatory issues must be addressed to ensure effective and safe clinical applications.

This review discusses the role of extracellular vesicles in psoriasis pathogenesis and their potential as therapeutic agents or drug delivery systems, but it reports no new clinical findings.

In this review, the authors highlight the crucial role of mesenchymal stem cells in dermatologic therapies, noting their potential to enhance skin structure and appearance through regenerative mechanisms like inflammation induction, angiogenesis, and recruitment of tissue-specific progenitors.

This review highlights the potential of exosomes, particularly those derived from mesenchymal stromal cells, for treating skin conditions and regeneration, but it also identifies challenges in their production and application.

This review explores the current and experimental therapies for chronic wounds, emphasizing the potential of cellular and immunotherapies in addressing these persistent conditions, but notes a shortage of comprehensive studies on their effectiveness.

This review summarizes recent findings on the role of mesenchymal stem cell-derived exosomal microRNAs in skin regeneration and rejuvenation, discussing their potential for treating skin damage and aging, and exploring bioengineering methods to enhance therapeutic effects.

This review examines the mechanisms, recent findings, and strategies to enhance mesenchymal stem cells' therapeutic effects in skin wound healing, but reports no new research results.