Histological and Molecular Restoration of Type VII Collagen in Recessive Dystrophic Epidermolysis Bullosa Mouse Skin by Topical Injection of Keratinocyte-Like Cells Differentiated from Human Adipose-Derived Mesenchymal Stromal Cells
May 2024
in “
Journal of Dermatological Science
”
Studysummary In this study, KC-AD-MSCs were found to increase COL7 deposition and anchoring fibril formation at the dermal-epidermal junction in a RDEB mouse model, suggesting potential for improving skin integrity in recessive dystrophic epidermolysis bullosa patients.
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