Efficient Genome Editing Using CRISPR/Cas9 Ribonucleoprotein Approach in iPS Cells for Recessive Dystrophic Epidermolysis Bullosa

    J. Jacków, Zongyou Guo, Hasan Erbil Abaci, Y. Doucet, Jung U Shin, C. Hansen, Yudai Kabata, Satoru Shinkuma, Julio C. Salas‐Alanís, A. M. Christiano
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    Studysummary This study demonstrated that gene-corrected 3D skin constructs from RDEB patient-derived iPSCs, grafted onto immunocompetent mice, showed normal collagen VII expression after two months.
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