Different Polyamine Levels in the Vertex and Occipital Hair of Pattern Hair Loss Patients

    September 2019 in “ Journal of Investigative Dermatology
    K. Kim, Bong Chul Chung, Y. Lee, J. Lee, Kweon-Eui Hong, Bark Lynn Lew, Woo Young Sim
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    TLDR People with pattern hair loss have higher polyamine levels in the top of their head compared to the back.
    The study examined the role of polyamines in pattern hair loss by measuring their levels in different scalp regions. Polyamines, associated with hair follicle proliferation, were found to be higher in the vertex region compared to the occipital region in patients with pattern hair loss. This indicates increased cellular proliferation in the vertex, the common starting point for pattern baldness. The findings suggest that polyamine levels in hair could be used as biomarkers for diagnosing and predicting the course of pattern baldness. However, the study did not disclose the number of participants or specific polyamine level data in the summary provided.
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