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    Glossary Dermal-Epidermal Junction

    interface where the epidermis connects to the dermis

    The Dermal-Epidermal Junction (DEJ) is a critical area of skin where the outer layer (epidermis) connects to the underlying layer (dermis). This junction plays a vital role in maintaining skin integrity, facilitating nutrient exchange, and supporting cellular communication. It is essential for wound healing and overall skin health, and its degradation can lead to various skin disorders.

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    1. Novel approaches to characterize age‐related remodelling of the dermal‐epidermal junction in 2D, 3D and <i>in vivo</i> Skin research and technology · 2016 · 30 citations
    2. The Fraser Complex Proteins (Frem1, Frem2, and Fras1) Can Form Anchoring Cords in the Absence of AMACO at the Dermal–Epidermal Junction of Mouse Skin International journal of molecular sciences · 2023 · 1 citations
    3. 1327 Effect of ginsenoside Rd on dermal epidermal junction in fibroblast Journal of Investigative Dermatology · 2018
    4. Characterization of the epidermal-dermal junction in hiPSC-derived skin organoids Stem cell reports · 2022 · 14 citations
    5. 565 hiPSC-derived skin organoids as tools for disease modelling: characterization of the epidermal-dermal junction Journal of Investigative Dermatology · 2022
    6. 918 Skin morphogenesis by coupling biochemical-bioelectric signals: Calcium oscillations coordinate dermal cell movement by epidermis-derived SHH signaling during feather bud orientation Journal of Investigative Dermatology · 2019
    7. Expression of laminin, type IV collagen and fibronectin molecules is related to embryonal skin and epidermal appendage morphogenesis. PubMed · 2001 · 10 citations
    8. 0873 Modeling junctional epidermolysis bullosa using tissue-engineered skin substitutes Journal of Investigative Dermatology · 2025
    9. Direct conversion of mouse and human fibroblasts to functional melanocytes by defined factors Nature Communications · 2014 · 66 citations
    10. Changes in fibronectin, laminin and type IV collagen distribution relate to basement membrane restructuring during the rat vibrissa follicle hair growth cycle. PubMed · 1992 · 45 citations
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    1. Comprehensive Microneedling Guide Reddit · 19 Aug 2022
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