Application and Prospect of Mesenchymal Stem Cells in the Field of Skin
December 2025
in “
Academic Journal of Science and Technology
”
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Studysummary This review explores the potential of mesenchymal stem cells in skin regeneration and rejuvenation, highlighting their ability to modulate immune response and enhance extracellular matrix strength but does not provide new clinical evidence. Our plain-language summary of this paper — not a Tressless recommendation.
Mesenchymal stem cells (MSCs) are promising for skin regeneration and rejuvenation due to their immunomodulatory and paracrine signaling properties. They aid wound healing by inhibiting excessive immune activities and secreting growth factors and cytokines. MSCs are easily extracted from bone marrow, adipose tissue, and umbilical cord tissue, making them practical for clinical use. In skin aging, MSCs help by synthesizing collagen and elastin to strengthen the extracellular matrix (ECM) and reducing proteins that break down the ECM. The potential for MSCs in skin care includes standardizing products and protocols, promoting personalized treatments, and ensuring ethical sourcing and safety.
