Mesenchymal Stem Cells for the Treatment of Skin Diseases

    January 2017 in “ AIMS cell and tissue engineering ”
    Toshio Hasegawa, Shigaku Ikeda
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    TLDR Mesenchymal stem cells show promise for treating various skin conditions and may help regenerate hair.
    The document from 6 years ago discussed the potential of mesenchymal stem cells (MSCs) in treating various skin conditions, including large vitiligo lesions, scarring alopecia, and androgenic alopecia. MSCs, derived from tissues like bone marrow and adipose tissues, can differentiate into multiple cell types, including keratinocytes, which are crucial for wound healing. The immunomodulatory properties of MSCs make them potentially useful for treating inflammatory and autoimmune skin diseases. The study suggested that MSCs could be a novel cell source for hair regeneration. MSCs were also shown to alleviate recessive dystrophic epidermolysis bullosa in both animal models and human subjects. However, the optimal method for administering MSCs was still debatable.
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