Novel Therapies for Alopecia Areata: The Era of Rational Drug Development

    December 2017 in “ The Journal of Allergy and Clinical Immunology ”
    Etienne C.E. Wang, Zhijun Dai, Angela M. Christiano
    Studysummary This review discusses the evolution of alopecia areata treatments towards more targeted therapies and reports no new clinical results, emphasizing cooperation between clinicians and scientists in understanding the disease's pathophysiology.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 49

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    7. Tofacitinib for the Treatment of Severe Alopecia Areata and Variants: A Study of 90 Patients Journal of The American Academy of Dermatology · 2016
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    9. Safety and Efficacy of the JAK Inhibitor Tofacitinib Citrate in Patients with Alopecia Areata JCI insight · 2016
    10. Oral Ruxolitinib Induces Hair Regrowth in Patients with Moderate-to-Severe Alopecia Areata JCI insight · 2016
    11. Successful Treatment of Pediatric Alopecia Areata of the Scalp Using Topical Bimatoprost Pediatric Dermatology · 2016
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    13. Genomewide Analysis of Copy Number Variants in Alopecia Areata in a Central European Cohort Reveals Association with MCHR2 Experimental Dermatology · 2016
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    15. ULBP3: A Marker for Alopecia Areata Incognita Archives of Dermatological Research · 2016
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    27. The PDE4 Inhibitor, Apremilast, Suppresses Experimentally Induced Alopecia Areata in Human Skin In Vivo Journal of Dermatological Science · 2014
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    45. Apoptosis Resistance in Peripheral Blood Lymphocytes of Alopecia Areata Patients Journal of Autoimmunity · 2004
    46. Clobetasol Propionate 0.05% Under Occlusion in the Treatment of Alopecia Totalis/Universalis Journal of the American Academy of Dermatology · 2003
    47. Hypertrichosis and Increased Pigmentation of Eyelashes and Adjacent Hair in the Region of the Ipsilateral Eyelids of Patients Treated with Unilateral Topical Latanoprost American Journal of Ophthalmology · 1997
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    Related research 3

    1. Twenty Nail Dystrophy with Alopecia Areata in an Atopic Child International journal of research in dermatology · 2019
    2. Oral Tofacitinib: A Promising Treatment in Atopic Dermatitis, Alopecia Areata, and Vitiligo Clinical and Experimental Dermatology · 2017
    3. Vitiligo After Diphencyprone for Alopecia Areata Dermatology Research and Practice · 2010