Reversal of Alopecia Universalis by Tofacitinib: A Case Report

    November 2016 in “ Annals of Internal Medicine ”
    Morton Scheinberg, Sineida Berbert Ferreira
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    TLDR Tofacitinib, an arthritis drug, helped hair growth in alopecia universalis but long-term safety needs more research.
    The document from 2016 reported on the use of tofacitinib citrate, a drug approved for rheumatoid arthritis, in treating alopecia universalis. It described two cases where patients experienced progressive hair growth after prolonged administration of tofacitinib, with no adverse events noted after 9 months. Despite these positive outcomes, the authors warned of potential serious side effects from long-term use of Janus kinase inhibitors and called for clinical trials to assess the treatment's efficacy and safety for alopecia universalis. The exact number of participants was not provided.
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      in Chat  3 upvotes 7 months ago
      A 23-year-old male is experiencing diffuse hair loss and miniaturization, possibly due to high IGE levels after using tofacitinib. He seeks advice and has not yet consulted a dermatologist.

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      in Treatment  2 upvotes 4 months ago
      The user is using finasteride 1mg every other day and seeks a topical solution excluding minoxidil. They are considering various combinations of ingredients like finasteride, dutasteride, and tofacitinib, with options for nourishing oils and other additives.

      community Topical solution recommendation

      in Product  1 upvotes 4 months ago
      The user is using finasteride 1mg every other day and seeks a topical solution to complement it, excluding minoxidil. They are considering various combinations of ingredients like finasteride, dutasteride, and tofacitinib, with options for nourishing oils and other additives.

      community 22F. Should I even bother getting a biopsy? Is there any point?

       7 upvotes 9 years ago
      A woman who has been experiencing hair loss for several years, and her question of whether there is any benefit to getting a biopsy to check if it's AGA or diffuse alopecia areata when no cure or very effective treatment exists. Treatments such as spironolactone and Minoxidil/finasteride/RU58841 have previously been discussed.

      community No hair, don't care! [24/F] :)

       58 upvotes 9 years ago
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