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GlossaryAlefacept

biologic drug that targets T-cells in autoimmune conditions

Alefacept is a biologic medication that was used to treat moderate to severe plaque psoriasis, an autoimmune skin condition. It works by targeting and reducing the activity of specific immune cells (T-cells) that are involved in the inflammatory process of psoriasis. Although it was effective for some patients, it has been discontinued in many markets due to the availability of newer treatments.

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research Treatment of Generalized Lichen Planus With Alefacept

52 citations, February 2006 in “Archives of Dermatology”

Alefacept may effectively treat severe lichen planus, with patients showing significant improvement and no side effects.

research Alefacept for Severe Alopecia Areata: A Multicenter, Double-Blind, Randomized, Placebo-Controlled Clinical Trial

43 citations, November 2009 in “Archives of dermatology”

Alefacept does not effectively treat severe alopecia areata.

research Alefacept for Alopecia Areata

33 citations, December 2005 in “Archives of dermatology”

Alefacept showed some effectiveness for alopecia areata but needs more research.

research Alefacept for Severe Alopecia Areata: A Randomized, Double-Blind, Placebo-Controlled Study

3 citations, January 2011 in “Yearbook of Dermatology and Dermatologic Surgery”

research Pediatric Dermatology

July 2003 in “Journal of Cutaneous Medicine and Surgery”

Skin problems are common in Bangladesh due to arsenic, prompt treatment of diabetic foot ulcers is crucial, maternal transmission causes most neonatal herpes, treatments for pediatric vasculitis are effective, the chickenpox vaccine works, more frequent UVB therapy helps psoriasis, certain jobs increase hand dermatitis risk, monoclonal antibodies treat psoriasis well, lifestyle affects psoriasis, alefacept improves psoriasis, imiquimod cream partially clears basal cell carcinoma, and iron may not help chronic hair loss.

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