Search
for

    GlossaryAlefacept

    biologic drug that targets T-cells in autoimmune conditions

    Alefacept is a biologic medication that was used to treat moderate to severe plaque psoriasis, an autoimmune skin condition. It works by targeting and reducing the activity of specific immune cells (T-cells) that are involved in the inflammatory process of psoriasis. Although it was effective for some patients, it has been discontinued in many markets due to the availability of newer treatments.

    Related Terms

    Sort by

    Research

    30 / 89 results
      Internal Medicine: Retrospective Review of 120 Patients Over a 10-Year Period

      research Internal Medicine: Retrospective Review of 120 Patients Over a 10-Year Period

      July 2003 in “Journal of Cutaneous Medicine and Surgery”
      Certain drugs can cause skin lupus, but stopping the drug usually helps. Vaccines work against smallpox, genital herpes, and a type of human papillomavirus. More frequent light therapy clears psoriasis faster. Certain treatments work for psoriasis and dermatitis. A specific cream effectively treats a type of skin cancer. Low iron levels aren't directly linked to chronic hair loss.
      Alefacept for Alopecia Areata

      research Alefacept for Alopecia Areata

      33 citations, December 2005 in “Archives of dermatology”
      Alefacept showed some effectiveness for alopecia areata but needs more research.
      Dermatological Drugs, Topical Agents, And Cosmetics

      research Dermatological Drugs, Topical Agents, And Cosmetics

      1 citations, January 2005 in “Side effects of drugs annual”
      The document concluded that various dermatological treatments have different effectiveness and side effects, with some causing irritation, allergic reactions, or systemic effects.
      Cancer

      research Cancer

      July 2003 in “Journal of Cutaneous Medicine and Surgery”
      Some medications can improve skin conditions, while lifestyle factors like smoking and drinking may worsen them; treatments like monoclonal antibodies and imiquimod cream show promise for certain skin diseases.
      Psoriasis, Acne, and Disorders of Keratinization

      research Psoriasis, Acne, and Disorders of Keratinization

      July 2003 in “Journal of Cutaneous Medicine and Surgery”
      Treating psoriasis with UVB light three times a week is faster than twice a week, and certain medications and lifestyle factors affect psoriasis treatment outcomes.
      Pediatric Dermatology

      research Pediatric Dermatology

      July 2003 in “Journal of Cutaneous Medicine and Surgery”
      Skin problems are common in Bangladesh due to arsenic, prompt treatment of diabetic foot ulcers is crucial, maternal transmission causes most neonatal herpes, treatments for pediatric vasculitis are effective, the chickenpox vaccine works, more frequent UVB therapy helps psoriasis, certain jobs increase hand dermatitis risk, monoclonal antibodies treat psoriasis well, lifestyle affects psoriasis, alefacept improves psoriasis, imiquimod cream partially clears basal cell carcinoma, and iron may not help chronic hair loss.
      HIV, Fungal, and Infectious Diseases

      research HIV, Fungal, and Infectious Diseases

      July 2003 in “Journal of Cutaneous Medicine and Surgery”
      The document concludes that various treatments for skin conditions are effective, but some require further research, and certain factors like gender and lifestyle can influence disease outcomes.
      Bullous/Mucous Membrane

      research Bullous/Mucous Membrane

      July 2003 in “Journal of Cutaneous Medicine and Surgery”
      High blood pressure drugs often cause skin lupus, stopping the drug usually helps. A vaccine helps prevent genital herpes and HPV-16. More frequent light therapy clears psoriasis faster. No link was found between low iron and chronic hair loss.
      Advances in Hair Diseases

      research Advances in Hair Diseases

      5 citations, November 2008 in “Advances in Dermatology”
      The review highlights the importance of stem cells in hair health and suggests new treatment strategies for hair loss conditions.
      Surgery And Laser

      research Surgery And Laser

      July 2003 in “Journal of Cutaneous Medicine and Surgery”
      Various skin conditions like cutaneous lupus erythematosus, psoriasis, and basal cell carcinoma can be effectively treated with antihypertensive agents, NB-UVB phototherapy, and imiquimod cream respectively. Vaccines are effective against genital herpes and HPV-16 infection. Early intervention is crucial for conditions like diabetic foot ulcers and neonatal herpes. Certain dyes can cause hand dermatitis, and there's a link between smoking/drinking and psoriasis in men. No direct link was found between low iron levels and chronic hair loss in women.
      Wound Healing and Hair

      research Wound Healing and Hair

      July 2003 in “Journal of Cutaneous Medicine and Surgery”
      Certain drugs can cause lupus, stopping these drugs is the main treatment. NB-UVB phototherapy clears psoriasis faster when applied three times a week. Monoclonal antibodies and oral pimecrolimus are effective in treating psoriasis. Smoking and drinking are linked to psoriasis in men. No direct link between low iron and hair loss was found. Vaccines are effective against genital herpes and human papillomavirus type 16.
      Treatment Options for Alopecia Areata

      research Treatment Options for Alopecia Areata

      4 citations, September 2011 in “Expert Review of Dermatology”
      Various treatments exist for alopecia areata, but none are completely satisfactory; choice depends on age, disease extent, and preference.
      Alopecia Areata: A Review of Disease Pathogenesis

      research Alopecia Areata: A Review of Disease Pathogenesis

      191 citations, May 2018 in “British journal of dermatology/British journal of dermatology, Supplement”
      Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.