Summary of the Preceding Three Alopecia Areata Research Summits: What’s Past Is Prologue

December 2013 in “ The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings ”

David A. Norris

alopecia areata National Alopecia Areata Registry genetic studies T cells natural killer cells autoimmune diseases immune privilege hair follicles AA NAAR

TLDR New treatments and strategies are needed for Alopecia Areata, focusing on immune response and better trial designs.

The document summarized the outcomes of three research summits organized by the National Alopecia Areata Foundation (NAAF) between 2008 and 2010. The first summit in 2008 focused on evaluating the progress of alopecia areata (AA) research and emphasized the importance of the National Alopecia Areata Registry (NAAR) for genetic studies. The second summit in 2009 concentrated on immunology, identifying key areas for future research, such as the role of T cells and natural killer cells in AA. The third summit in 2010 aimed to develop a clinical research network to expedite new treatments, exploring drugs used in other autoimmune diseases. These summits laid the groundwork for future research directions, including the development of new animal models, targeting specific immune cells, and restoring immune privilege in hair follicles.

View this study on jidsponline.org →

Discuss this study in the Community →

Research cited in this study

1 / 1 results

research Genome-Wide Association Study in Alopecia Areata Implicates Both Innate and Adaptive Immunity

717 citations, June 2010 in “Nature”

Alopecia areata involves both innate and adaptive immunity, with specific genes linked to the disease.

Related Community Posts Join

6 / 1000+ results

community Can I punch someone if they make fun of my hair loss, just like Will Smith did?

in Chat 448 upvotes 3 years ago

Hair loss's social impact, focusing on Will Smith defending Jada Pinkett Smith's alopecia. The conversation highlights double standards between men and women experiencing hair loss and emphasizes empathy.

community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

in Research 830 upvotes 10 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community Article of all potential future cures

in Treatment 25 upvotes 1 month ago

Ritlecitinib and PP405 show promise for hair regrowth. Diagnosing the cause of hair loss is crucial before treatment.

community PP405: The Ultimate Hair Loss Drug for Complete Hair Growth

in Research/Science 206 upvotes 5 months ago

PP405 is a new hair loss treatment in phase 2 trials that may promote hair growth by increasing lactate production and activating hair follicle stem cells. It could potentially replace hormone-disrupting treatments like Minoxidil and finasteride.

community Why is it barely impossible to find balding South Korean men

in Research/Science 247 upvotes 1 year ago

The post discusses the rarity of baldness among South Korean men. Users suggest this could be due to early treatment, high beauty standards, accessibility of healthcare, and genetics. Treatments like finasteride and dutasteride are commonly used, and hair transplants are also popular.

community find a cure for this shit already

in Chat 208 upvotes 4 years ago

Treatments used to prevent and treat male pattern baldness, the difficulty in finding a permanent cure for hair loss, and the potential financial motivations of companies not wanting to find a cure.

Related Research

1 / 1 results

research Twenty Nail Dystrophy with Alopecia Areata in an Atopic Child

April 2019 in “International journal of research in dermatology”

A child with rough nails also had hair loss and allergies.