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Glossary Abatacept

medication that inhibits T-cell activation to treat autoimmune diseases

Abatacept, also known by the brand name Orencia, is a medication used to treat autoimmune conditions such as rheumatoid arthritis and certain types of juvenile idiopathic arthritis. It works by inhibiting the activation of T-cells, a type of white blood cell that plays a key role in the immune response, thereby reducing inflammation and preventing the immune system from attacking healthy tissues.

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Research

5 / 105 results

research 320 An open label clinical trial of Abatacept (CTLA4-Ig) for alopecia areata

1 citations , April 2017 in “Journal of Investigative Dermatology”

Abatacept may help some people with alopecia areata regrow hair.

research Functional Interpretation of Genome-Wide Association Study Evidence in Alopecia Areata

55 citations , October 2015 in “Journal of Investigative Dermatology”

Alopecia areata is linked to immune-related genes, suggesting JAK inhibitors as a potential treatment.

research Emerging treatments in alopecia

47 citations , October 2014 in “Expert Opinion on Emerging Drugs”

This review discusses emerging treatments and mechanisms for alopecia, highlighting potential therapies like janus kinase inhibitors and advances in stem-cell technology, but reports no new experimental results.

research The Changing Landscape of Alopecia Areata: The Translational Landscape

16 citations , June 2017 in “Advances in Therapy”

This review summarizes recent research on alopecia areata, highlighting advances in targeted therapies due to improved understanding of its immunopathogenesis, though it reports no new clinical results.

research ACTH as first line treatment for acute calcium pyrophosphate crystal arthritis in 14 hospitalized patients

14 citations , June 2013 in “Joint Bone Spine”

This review discusses current anti-inflammatory treatment options for calcium pyrophosphate crystal deposition disease (CPPD) and highlights the lack of crystal-targeted therapies, emphasizing the need for more research to guide treatment.

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2 / 801 results

learn Tofacitinib

a JAK inhibitor for alopecia areata and other autoimmune conditions

learn Baricitinib

JAK inhibitor that reduces inflammation and immune attacks on hair follicles, leading to potential hair regrowth, especially in alopecia areata cases

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