Transcriptome Sequencing Reveals Key Genes Associated With Hair Follicle Development in Qianhua Mutton Merino

    December 2025 in “ Frontiers in Veterinary Science ”
    Limin Sun
    Studysummary In this study, researchers explored hair follicle development in Qianhua Mutton Merino sheep, identifying key genes like KRT27 and IGF-2 that impact this process, with findings suggesting significant molecular changes as sheep mature from newborn to one year old.
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    Research cited in this study 24

    1. Fgf21 Deficiency Delays Hair Follicle Cycling and Modulates miRNA–Target Gene Interactions in Mice Biology · 2025
    2. Effects of Oral Minoxidil on Serum VEGF and Hair Regrowth in Androgenetic Alopecia Acta Dermatovenerologica Alpina Pannonica et Adriatica · 2025
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    6. miR-29a-5p Inhibits Prenatal Hair Placode Formation Through Targeting EDAR by ceRNA Regulatory Network Frontiers in Cell and Developmental Biology · 2022
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    8. Integration Analysis of Transcriptome and Proteome Reveals the Mechanisms of Goat Wool Bending Frontiers in cell and developmental biology · 2022
    9. Skin Transcriptome Analysis Identifies Key Genes Underlying Fur Development in Chinese Tan Sheep During Birth and Er-Mao Periods Gene · 2022
    10. Pyridoxine Regulates Hair Follicle Development via the PI3K/Akt, Wnt, and Notch Signalling Pathways in Rex Rabbits Animal nutrition · 2021
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    15. Quercitrin Stimulates Hair Growth with Enhanced Expression of Growth Factors via Activation of MAPK/CREB Signaling Pathway Molecules · 2020
    16. Analysis of lncRNAs Expression Profiles in Hair Follicles of Hu Sheep Lambskin Animals · 2020
    17. Migration Inhibitory Factor in Conditioned Medium from Human Umbilical Cord Blood-Derived Mesenchymal Stromal Cells Stimulates Hair Growth Cells · 2020
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    21. A Role for the TGF-β/BMP Co-Receptor Endoglin in the Molecular Oscillator That Regulates the Hair Follicle Cycle Journal of Molecular Cell Biology · 2018
    22. Melatonin Promotes Cashmere Goat (Capra Hircus) Secondary Hair Follicle Growth: A View from Integrated Analysis of Long Non-Coding and Coding RNAs Cell Cycle · 2018
    23. Transcriptome Reveals Long Non-Coding RNAs and mRNAs Involved in Primary Wool Follicle Induction in Carpet Sheep Fetal Skin Frontiers in physiology · 2018
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