Pyridoxine Regulates Hair Follicle Development via the PI3K/Akt, Wnt, and Notch Signalling Pathways in Rex Rabbits

    October 2021 in “ Animal nutrition ”
    Gongyan Liu, Guangcun Cheng, Zhang Yongcui … Fuchang Li
    Studysummary This study found that dietary pyridoxine increased hair follicle density in Rex rabbits by activating PI3K/Akt, Wnt, and Notch signaling pathways, which may promote hair growth and delay telogen onset.
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    Research cited in this study 7

    1. Epidermal Growth Factor Promotes Proliferation of Dermal Papilla Cells via Notch Signaling Pathway Biochimie · 2016
    2. Dermal Papilla Cell Number Specifies Hair Size, Shape, and Cycling, and Its Reduction Causes Follicular Decline Development · 2013
    3. HMSCs Possess the Potential to Differentiate Into DP Cells In Vivo and In Vitro Cell Biology International Reports · 2012
    4. Scratching the Surface of Skin Development Nature · 2007
    5. Bone Morphogenetic Protein Signaling Inhibits Hair Follicle Anagen Induction by Restricting Epithelial Stem/Progenitor Cell Activation and Expansion Stem Cells · 2006
    6. Molecular Mechanisms Regulating Hair Follicle Development ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2002
    7. Inhibition of BMP Signaling Affects Growth and Differentiation in the Anagen Hair Follicle The EMBO Journal · 2000