Transcriptomic Analysis Reveals AKT1 Upregulation in Inner Mongolian Cashmere Goats at 12 and 15 Months of Age

    July 2026 in “ Veterinary Sciences ”
    Muhammad Zain Ghauri, Ayesha Zafar, M Khuzema Niaz … Dejun Ji
    Studysummary This study explored the decline in cashmere production in Inner Mongolian cashmere goats through RNA-seq analysis, finding that AKT1 expression and related signaling pathways are age-dependent, with peak AKT1 upregulation at 12 months aligning with peak cashmere production.
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    Research cited in this study 18

    1. Comparative Skin Transcriptomics Reveals Key Regulators of Cashmere Fiber Production in Inner Mongolian Goats Animals · 2026
    2. Comprehensive Analysis of Differences in Cashmere Production Performance in Liaoning Cashmere Goats Using Metabolomics and Transcriptomics Frontiers in Veterinary Science · 2025
    3. Transcriptome Sequencing Reveals Key Genes Associated With Hair Follicle Development in Qianhua Mutton Merino Frontiers in Veterinary Science · 2025
    4. Transcriptome Sequencing Reveals the Expression Profiles of lncRNAs and mRNAs in Goat Skin Tissues With Different Types of Wool Coats Scientific Reports · 2025
    5. Molecular Mechanisms Underlying Cashmere Quality Differences Between Jiangnan Cashmere Goats and Changthangi Pashmina Goats Frontiers in Veterinary Science · 2025
    6. Whole-Transcriptome RNA Sequencing Reveals Global Expression Dynamics and ceRNA Regulatory Networks Related to Hair Follicle Development and Melanogenesis in Goats Animal Bioscience · 2025
    7. Melatonin Promotes Proliferation of Inner Mongolia Cashmere Goat Hair Follicle Papilla Cells Through Wnt10b Genomics · 2024
    8. Hair Follicle Development and Cashmere Traits in Albas Goat Kids Animals · 2023
    9. Identification of Key Pathways and Genes That Regulate Cashmere Development in Cashmere Goats Mediated by Exogenous Melatonin Frontiers in veterinary science · 2022
    10. Identification of Genes Related to Hair Follicle Cycle Development in Inner Mongolia Cashmere Goat by WGCNA Frontiers in Veterinary Science · 2022
    11. Morphogenesis, Growth Cycle, and Molecular Regulation of Hair Follicles Frontiers in Cell and Developmental Biology · 2022
    12. The Fiber Diameter Traits of Tibetan Cashmere Goats Are Governed by the Inherent Differences in Stress, Hypoxic, and Metabolic Adaptations: An Integrative Study of Proteome and Transcriptome BMC Genomics · 2022
    13. Shedding Light on Cashmere Goat Hair Follicle Biology: From Morphology Analyses to Transcriptomic Landscape BMC genomics · 2020
    14. Skin Transcriptome Reveals the Periodic Changes in Genes Underlying Cashmere Follicle Transition in Cashmere Goats BMC genomics · 2020
    15. Transcriptomic Analysis Reveals Critical Genes for the Hair Follicle of Inner Mongolia Cashmere Goat from Catagen to Telogen PloS one · 2018
    16. Melatonin Promotes Cashmere Goat (Capra Hircus) Secondary Hair Follicle Growth: A View from Integrated Analysis of Long Non-Coding and Coding RNAs Cell Cycle · 2018
    17. Signaling Involved in Hair Follicle Morphogenesis and Development International Journal of Molecular Sciences · 2014
    18. Transcriptome Sequencing Reveals Differences Between Primary and Secondary Hair Follicle-Derived Dermal Papilla Cells of the Cashmere Goat PLoS ONE · 2013