Comprehensive Analysis of Differences in Cashmere Production Performance in Liaoning Cashmere Goats Using Metabolomics and Transcriptomics

    December 2025 in “ Frontiers in Veterinary Science ”
    Bing De Luo, Meiqi Wang, Di Han … Wei Ma
    Studysummary This study found that PT-LCG extends hair follicle activity and promotes continuous cashmere growth by enhancing lipid synthesis, remodeling the extracellular matrix, and modulating inflammatory signaling, offering insights into improving cashmere yield and quality through molecular breeding.
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    Research cited in this study 7

    1. Hair Growth Promoting Effect of 4HGF Encapsulated with PGA Nanoparticles by β-Catenin Activation and Related Cell Cycle Molecules International Journal of Molecular Sciences · 2019
    2. Disruption of FGF5 in Cashmere Goats Using CRISPR/Cas9 Results in More Secondary Hair Follicles and Longer Fibers PLoS ONE · 2016
    3. Signaling Couples Hair Follicle Stem Cell Quiescence With Reduced Histone H3 K4/K9/K27me3 for Proper Tissue Homeostasis Nature communications · 2016
    4. A Microarray-Based Analysis Reveals That a Short Photoperiod Promotes Hair Growth in the Arbas Cashmere Goat PLoS ONE · 2016
    5. Differential Response of Epithelial Stem Cell Populations in Hair Follicles to TGF-Beta Signaling Developmental Biology · 2012
    6. P63 Regulates Human Keratinocyte Proliferation Via MYC-Regulated Gene Network and Differentiation Commitment Through Cell Adhesion-Related Gene Network Journal of Biological Chemistry · 2011
    7. Hair Follicular Expression and Function of Group X Secreted Phospholipase A2 in Mouse Skin Journal of Biological Chemistry · 2011