Multi-Omics Analysis of Functional Substances and Expression Verification in Cashmere Fineness

    November 2023 in “ BMC genomics ”
    Yanan Xu, Yu Zhang, Yuting Qin … Zeying Wang
    Studysummary Using a multi-omics analysis, this study identified key regulators like PLA2G12A, KRT79, and prostaglandin B2 that influence cashmere fineness, providing crucial data for understanding the molecular mechanisms behind this trait in Liaoning cashmere goats.
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    Research cited in this study 13

    1. Keratin 79 Is a PPARA Target That Is Highly Expressed by Liver Damage Biochemical and biophysical research communications · 2023
    2. M6a Methylation Analysis of Differentially Expressed Genes in Skin Tissues of Coarse and Fine Type Liaoning Cashmere Goats Frontiers in Genetics · 2020
    3. Alkaline Ceramidase 1 Protects Mice from Premature Hair Loss by Maintaining the Homeostasis of Hair Follicle Stem Cells Stem Cell Reports · 2017
    4. Molecular Characterization, Expression and Methylation Status Analysis of BMP4 Gene in Skin Tissue of Liaoning Cashmere Goat During Hair Follicle Cycle Genetica · 2016
    5. Keratin 79 Identifies a Novel Population of Migratory Epithelial Cells That Initiates Hair Canal Morphogenesis and Regeneration Development · 2013
    6. The Prostamide-Related Glaucoma Therapy, Bimatoprost, Offers a Novel Approach for Treating Scalp Alopecias The FASEB Journal · 2012
    7. Identification and Sequence Analysis of the Keratin-Associated Protein 24-1 (KAP24-1) Gene Homologue in Sheep Gene · 2012
    8. A Randomized Double-Blind Placebo-Controlled Pilot Study to Assess the Efficacy of a 24-Week Topical Treatment by Latanoprost 0.1% on Hair Growth and Pigmentation in Healthy Volunteers with Androgenetic Alopecia Journal of The American Academy of Dermatology · 2011
    9. LPA-Producing Enzyme PA-PLA1α Regulates Hair Follicle Development by Modulating EGFR Signaling The EMBO Journal · 2011
    10. Characterization of an In Vivo Model for the Study of Eyelash Biology and Trichomegaly: Mouse Eyelash Morphology, Development, Growth Cycle, and Anagen Prolongation by Bimatoprost British journal of dermatology/British journal of dermatology, Supplement · 2010
    11. Characterization and Expression Analysis of KAP7.1 and KAP8.2 Genes in Liaoning New-Breeding Cashmere Goat Hair Follicles Molecular biology reports · 2010
    12. Prostaglandin Metabolism in Human Hair Follicle Experimental Dermatology · 2007
    13. Hard and Soft Principles Defining the Structure, Function, and Regulation of Keratin Intermediate Filaments Current Opinion in Cell Biology · 2002

    Related research 1

    1. 10× Genomics Single-Cell Sequencing Reveals Differential Cell Types in Skin Tissues of Liaoning Cashmere Goats and Key Genes Potentially Related to the Fineness of Cashmere Fiber Research Square (Research Square) · 2020