TLDR lncRNAs influence cashmere fiber traits like diameter and color in goats.
The study investigated the roles of long non-coding RNAs (lncRNAs) in cashmere fiber production in Liaoning cashmere (LC) and Ziwuling black (ZB) goats in China, involving 12 goats in total. It identified 129 differentially expressed lncRNAs between the two breeds, with specific lncRNAs linked to fiber diameter and color regulation. The research highlighted the potential of lncRNAs in regulating cashmere fiber traits, with pathways related to fiber follicle development, cashmere fiber diameter, and color, such as the PPAR signaling pathway, metabolic pathways, and melanogenesis. The findings provided insights into the molecular mechanisms underlying cashmere fiber differences, potentially aiding in the improvement of cashmere quality through genetic and breeding strategies.
14 citations
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April 2022 in “Functional & Integrative Genomics” Key molecular interactions were identified that help understand hair follicle development in cashmere goats.
5 citations
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January 2021 in “Animal Production Science” Lipid metabolism affects wool fiber diameter in sheep.
17 citations
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June 2020 in “Animals” lncRNAs may regulate hair follicle development in Hu sheep.
26 citations
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April 2019 in “Genes” lncRNA XLOC_008679 and gene KRT35 affect cashmere fineness in goats.
37 citations
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May 2018 in “Frontiers in physiology” Certain RNA molecules are important for the development of wool follicles in sheep.
50 citations
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March 2018 in “BMC Genomics” Non-coding RNAs help control hair growth cycles in cashmere goats, suggesting ways to improve cashmere production.
129 citations
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October 2017 in “BMC Genomics” The study improved understanding of gene roles in cashmere goat hair growth, aiding future cashmere production.
16 citations
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January 2015 in “Genetics and Molecular Research” The research helps improve wool quality and aids human hair research.
6 citations
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June 2013 in “International Journal of Cosmetic Science” Lipids are crucial for maintaining hair structure and health.
55 citations
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January 2013 in “International Journal of Cosmetic Science” African hair's keratin structure is influenced by its higher lipid content.
