Transcriptome Sequencing Reveals the Expression Profiles of lncRNAs and mRNAs in Goat Skin Tissues With Different Types of Wool Coats

    May 2025 in “ Scientific Reports ”
    Peng Zhao, Hongyu Guo, Jieru Han … Li Zhang
    Studysummary In this study, researchers analyzed skin tissues from two types of Jinlan Cashmere Goats and identified crucial non-coding RNA mechanisms potentially impacting cashmere yield, revealing significant DE lncRNAs, mRNA expressions, and pathways relevant to cashmere quality improvement.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on nature.com →
    Discuss this study in the Community →

    Research cited in this study 39

    1. Insights from Tandem Mass Tag Proteomic Analysis on Protein Network Modification in Control of Yak Hair Follicle Cycle International Journal of Molecular Sciences · 2025
    2. Deciphering the Molecular Drivers for Cashmere/Pashmina Fiber Production in Goats: A Comprehensive Review Mammalian Genome · 2025
    3. Pathogenesis and Regenerative Therapy in Vitiligo and Alopecia Areata: Focus on Hair Follicle Frontiers in Medicine · 2025
    4. Comprehensive Analysis of the Expression Profiles of mRNA, lncRNA, circRNA, and miRNA in Primary Hair Follicles of Coarse Sheep Fetal Skin BMC Genomics · 2024
    5. Human Hair Graying Revisited: Principles, Misconceptions, And Key Research Frontiers Journal of Investigative Dermatology · 2023
    6. Signaling Pathways in Hair Aging Frontiers in cell and developmental biology · 2023
    7. Uncovering the Complex Relationship Between Balding, Testosterone, and Skin Cancers in Men Nature Communications · 2023
    8. Developmental Mapping of Hair Follicles in the Embryonic Stages of Cashmere Goats Using Proteomic and Metabolomic Construction Animals · 2023
    9. Mechanical Stimuli-Induced CCL2 Restores Adult Mouse Cells to Regenerate Hair Follicles Molecular Therapy — Nucleic Acids · 2023
    10. Hair Follicle Development and Cashmere Traits in Albas Goat Kids Animals · 2023
    11. The Regulation Mechanism Of Different Hair Types In Inner Mongolia Cashmere Goat Based On PI3K-AKT Pathway And FGF21 Journal of Animal Science · 2022
    12. Hair Follicle Morphogenesis During Embryogenesis, Neogenesis, and Organogenesis Frontiers in Cell and Developmental Biology · 2022
    13. Assessment of Hair and Cashmere Properties and Their Genetic Background of Several Goat Breeds in Southwest China Scientific reports · 2022
    14. Identification of Genes Related to Hair Follicle Cycle Development in Inner Mongolia Cashmere Goat by WGCNA Frontiers in Veterinary Science · 2022
    15. Klhl24-Mediated Hair Follicle Stem Cells Structural Disruption Causes Alopecia ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2022
    16. Intrinsic ROS Drive Hair Follicle Cycle Progression by Modulating DNA Damage and Repair and Subsequently Hair Follicle Apoptosis and Macrophage Polarization Oxidative Medicine and Cellular Longevity · 2022
    17. Emerging Role of Dermal White Adipose Tissue in Modulating Hair Follicle Development During Aging Frontiers in Cell and Developmental Biology · 2021
    18. The Roles of Non-Coding RNA in the Development and Regeneration of Hair Follicles: Current Status and Further Perspectives Frontiers in Cell and Developmental Biology · 2021
    19. Hormonal Effects on Hair Follicles International journal of molecular sciences · 2020
    20. Effect of Nutritional Restriction on the Hair Follicles Development and Skin Transcriptome of Chinese Merino Sheep Animals · 2020
    21. Immune Modulation of Hair Follicle Regeneration npj Regenerative Medicine · 2020
    22. PDGFA in Cashmere Goat: A Motivation for the Hair Follicle Stem Cells to Activate Animals · 2019
    23. Transcriptomic Analysis Reveals Critical Genes for the Hair Follicle of Inner Mongolia Cashmere Goat from Catagen to Telogen PloS one · 2018
    24. Types I and II Keratin Intermediate Filaments Cold Spring Harbor Perspectives in Biology · 2018
    25. Commensal Microbes and Hair Follicle Morphogenesis Coordinately Drive Treg Migration into Neonatal Skin Cell host & microbe · 2017
    26. Meta-Analysis Identifies Novel Risk Loci and Yields Systematic Insights into the Biology of Male-Pattern Baldness Nature communications · 2017
    27. A Microarray-Based Analysis Reveals That a Short Photoperiod Promotes Hair Growth in the Arbas Cashmere Goat PLoS ONE · 2016
    28. Differential Expression of Proteins Associated with the Hair Follicle Cycle: Proteomics and Bioinformatics Analyses PLOS ONE · 2016
    29. Leptin Controls Hair Follicle Cycling Experimental Dermatology · 2014
    30. Estrogen Leads to Reversible Hair Cycle Retardation Through Inducing Premature Catagen and Maintaining Telogen PLOS ONE · 2012
    31. Identification of Ectodysplasin Target Genes Reveals the Involvement of Chemokines in Hair Development ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2012
    32. Development of a DNA-Analytical Method for the Identification of Animal Hair Fibers in Textiles Textile Research Journal · 2009
    33. The Human Keratins: Biology And Pathology Histochemistry and Cell Biology · 2008
    34. Keratin 15 Promoter Targets Putative Epithelial Stem Cells in the Hair Follicle Bulge Journal of Investigative Dermatology · 2003
    35. Molecular Mechanisms Regulating Hair Follicle Development ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2002
    36. The Biology of Hair Follicles The New England Journal of Medicine · 1999
    37. Growth Factors and Cytokines in Hair Follicle Development and Cycling: Recent Insights from Animal Models and the Potentials for Clinical Therapy Molecular Medicine Today · 1996
    38. An Estrogen Receptor Pathway Regulates the Telogen-Anagen Hair Follicle Transition and Influences Epidermal Cell Proliferation Proceedings of the National Academy of Sciences of the United States of America · 1996
    39. Cytokines and Growth Factors Influence Hair Growth In Vitro: Possible Implications for the Pathogenesis and Treatment of Alopecia Areata Archives of Dermatological Research · 1996