Insights from Tandem Mass Tag Proteomic Analysis on Protein Network Modification in Control of Yak Hair Follicle Cycle

    February 2025 in “ International Journal of Molecular Sciences ”
    Shijie Li, Yan Cui, Sijiu Yu … Robert Niayale
    Studysummary This study identified key proteins, such as Sfrp1 and Ppard, involved in the complex and dynamic regulation of yak hair follicle growth and degeneration across different stages, offering insights into yaks' adaptation to highland environments.
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    Research cited in this study 24

    1. Histological Characteristics of Hair Follicles at Different Hair Cycle and In Vitro Modeling of Hair Follicle-Associated Cells of Yak (Bos Grunniens) Frontiers in veterinary science · 2023
    2. Studying Hair Growth Cycle and Its Effects on Mouse Skin Journal of Investigative Dermatology · 2023
    3. Epithelially Derived, Mitochondrial MPZL3 Negatively Regulates Murine and Human Hair Follicle Cycling Journal of Investigative Dermatology · 2023
    4. Regulation of Stem Cell Fate by HSPGs: Implication in Hair Follicle Cycling npj Regenerative Medicine · 2022
    5. Comparative Analysis of mRNA and miRNA Expression Between Dermal Papilla Cells and Hair Matrix Cells of Hair Follicles in Yak Cells · 2022
    6. Insights Into Male Androgenetic Alopecia Using Comparative Transcriptome Profiling: Hypoxia-Inducible Factor-1 and Wnt/Beta-Catenin Signalling Pathways British Journal of Dermatology · 2022
    7. Functional Hair Follicle Regeneration: An Updated Review Signal Transduction and Targeted Therapy · 2021
    8. Skin Transcriptome Reveals the Periodic Changes in Genes Underlying Cashmere Follicle Transition in Cashmere Goats BMC genomics · 2020
    9. Porosity at Different Structural Levels in Human and Yak Belly Hair and Its Effect on Hair Dyeing Molecules/Molecules online/Molecules annual · 2020
    10. DHT and E2 Synthesis-Related Proteins and Receptors Expression in Male Yak Skin During Different Hair Follicle Stages General and Comparative Endocrinology · 2019
    11. Deciphering the Molecular Morphology of the Human Hair Cycle: Wnt Signalling During the Telogen–Anagen Transformation British Journal of Dermatology · 2019
    12. TGF-β and HSP70 Profiles During Transformation of Yak Hair Follicles from Anagen to Catagen Stage Journal of cellular physiology · 2019
    13. Emerging Nonmetabolic Functions of Skin Fat Nature Reviews Endocrinology · 2018
    14. Expression Characteristics of BMP2, BMPR-IA, and Noggin in Different Stages of Hair Follicle in Yak Skin General and comparative endocrinology · 2017
    15. Activating Beta-Catenin Signaling in CD133-Positive Dermal Papilla Cells Increases Hair Inductivity FEBS Journal · 2016
    16. Pharmacologic Inhibition of JAK-STAT Signaling Promotes Hair Growth Science Advances · 2015
    17. Hair Follicle Dermal Stem Cells Regenerate the Dermal Sheath, Repopulate the Dermal Papilla, and Modulate Hair Type Developmental Cell · 2014
    18. VEGF Induces Proliferation of Human Hair Follicle Dermal Papilla Cells Through VEGFR-2-Mediated Activation of ERK Experimental Cell Research · 2012
    19. Adipocyte Lineage Cells Contribute to the Skin Stem Cell Niche to Drive Hair Cycling Cell · 2011
    20. Self-Organizing and Stochastic Behaviors During the Regeneration of Hair Stem Cells Science · 2011
    21. Activated KRAS Alters Epidermal Homeostasis of Mouse Skin, Resulting in Redundant Skin and Defective Hair Cycling Journal of Investigative Dermatology · 2010
    22. Distinguishing Mouse Strains by Proteomic Analysis of Pelage Hair Journal of Investigative Dermatology · 2009
    23. The Hair Follicle as an Estrogen Target and Source Endocrine Reviews · 2006
    24. Two Distinct Signaling Pathways in Hair Cycle Induction: Stat3-Dependent and Independent Pathways Proceedings of the National Academy of Sciences of the United States of America · 2000

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