Putting the Human Hair Follicle Cycle on the Map

January 2016 in “ Journal of Investigative Dermatology ”

Andrey A. Panteleyev

xenograft model human hair follicle cycle immunocompromised mice anagen hair follicles follicular morphology hair cycle biology hair cycle pathology hair cycle-modulating drugs hair growth disorders

TLDR The research created a model to understand human hair growth cycle, which can help diagnose and treat hair growth disorders and test potential hair growth drugs.

The 2015 document "Putting the Human Hair Follicle Cycle on the Map" developed a xenograft model to study the human hair follicle cycle by grafting human skin onto immunocompromised mice. This model was used to study over a thousand human anagen hair follicles, observing follicular morphology at 45 time points between days 2 and 402 after grafting. The study found this model useful for studying hair cycle biology and pathology, and for testing potential hair cycle-modulating drugs. The research also provided a guide for identifying the stages of the hair follicle cycle, crucial for diagnosing and treating hair growth disorders.

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