Histologic and Cell Kinetic Studies of Hair Loss and Subsequent Recovery Process of Human Scalp Hair Follicles Grafted onto Severe Combined Immunodeficient Mice
August 2000
in “
Journal of Investigative Dermatology
”
hair follicles severe combined immunodeficient mice dystrophic stage regeneration stage stable growth stage apoptosis keratin 19-positive cells keratin 19-negative cells BrdU-labeled cells inner root sheath hair shaft anagen hair follicles melanin incontinence stem cells secondary germ SCID mice BrdU
Studysummary This study found that when human hair follicles were grafted onto mice, they progressed through dystrophic stages and returned to normal growth, with stem cells aiding in recovery.
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