Identification of Key Pathways and Genes That Regulate Cashmere Development in Cashmere Goats Mediated by Exogenous Melatonin

    September 2022 in “ Frontiers in veterinary science ”
    Zhihong Liu, Zhichen Liu, Qing Mu … Yanhong Zhao
    Studysummary This study identified key genes and signaling pathways involved in cashmere goat hair follicle growth cycles, influenced by melatonin implantation, suggesting a basis for further research on melatonin's regulatory mechanism.
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    Research cited in this study 16

    1. Melatonin Regulates the Periodic Growth of Cashmere by Upregulating the Expression of Wnt10b and β-Catenin in Inner Mongolia Cashmere Goats Frontiers in genetics · 2021
    2. Identification of Potential Key Genes and Pathways Associated with the Pashmina Fiber Initiation Using RNA-Seq and Integrated Bioinformatics Analysis Scientific Reports · 2021
    3. Using WGCNA to Identify Hub Genes of Skin Hair Follicle Development in Fetal Stage of Inner Mongolia Cashmere Goat PloS one · 2020
    4. Melatonin Supplement Induced Hair Follicle Development in Offspring Rex Rabbits Journal of Animal Physiology and Animal Nutrition · 2020
    5. Skin Transcriptome Reveals the Periodic Changes in Genes Underlying Cashmere Follicle Transition in Cashmere Goats BMC genomics · 2020
    6. PI3K/Akt Signaling Pathway Is Essential for De Novo Hair Follicle Regeneration Stem Cell Research & Therapy · 2020
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    8. The Study on Biological Function of Keratin 26, a Novel Member of Liaoning Cashmere Goat Keratin Gene Family PloS one · 2016
    9. Disruption of FGF5 in Cashmere Goats Using CRISPR/Cas9 Results in More Secondary Hair Follicles and Longer Fibers PLoS ONE · 2016
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    11. Growth and Viability of Liaoning Cashmere Goat Hair Follicles During the Annual Hair Follicle Cycle Genetics and Molecular Research · 2014
    12. Exploring Differentially Expressed Genes by RNA-Seq in Cashmere Goat Skin During Hair Follicle Development and Cycling PloS one · 2013
    13. Epithelial Stem Cells And Implications For Wound Repair Seminars in Cell & Developmental Biology · 2012
    14. Effect of IGF-I on Hair Growth Is Related to the Anti-Apoptotic Effect of IGF-I and Up-Regulation of PDGF-A and PDGF-B Annals of Dermatology · 2012
    15. Molecular Principles of Hair Follicle Induction and Morphogenesis BioEssays · 2005
    16. Effect of Immunization Against Melatonin on Seasonal Fleece Growth in Feral Goats Journal of pineal research · 1992