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GlossaryPlatelet-Derived Growth Factor Receptor (PDGFR)

cell surface receptor that binds to growth factors for cell processes

Platelet-Derived Growth Factor Receptor (PDGFR) is a cell surface receptor that binds to platelet-derived growth factors (PDGFs). When PDGFs attach to PDGFR, it triggers a series of cellular processes, including cell growth, division, and survival. This receptor plays a crucial role in wound healing and the development of blood vessels, and its malfunction can be associated with various diseases, including cancers and fibrotic conditions.

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learn Platelet-Derived Growth Factor Beta Polypeptide

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research Platelet-Derived Growth Factor Signaling Modulates Adult Hair Follicle Dermal Stem Cell Maintenance and Self-Renewal

37 citations, April 2017 in “npj Regenerative Medicine”

PDGF signaling is crucial for maintaining and renewing hair follicle stem cells, which could help treat hair loss.

research Identification of Key Pathways and Genes That Regulate Cashmere Development in Cashmere Goats Mediated by Exogenous Melatonin

3 citations, September 2022 in “Frontiers in veterinary science”

Melatonin affects cashmere growth in goats by influencing stem cell and certain signaling pathways.

Regulation of Adipocyte Dedifferentiation at the Skin Wound Edge

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