TLDR A substance called Cell-free fat extract can effectively treat common hair loss by increasing hair growth and density.
The study evaluated the effectiveness of Cell-free fat extract (CEFFE) in treating Androgenetic alopecia (AGA), a common hair loss disease. The research involved five groups of male C57BL/6 mice (n=12 in each group) treated with different concentrations of CEFFE for 18 days. The results showed that CEFFE-treated mice had an increased hair growth rate and hair coverage percentage. CEFFE also promoted the proliferation of dermal papilla cells (DPCs), modulated the cell cycle arrest, inhibited apoptosis caused by dihydrotestosterone (DHT), reduced the intracellular concentration of DHT in DPCs, and downregulated the expression of androgen receptor (AR). The study concluded that CEFFE is a novel and effective treatment for AGA, increasing hair follicle density and hair growth rate through the DHT/AR pathway regulation and regional angiogenesis ability.View this study on stemcellres.biomedcentral.com →
Dihydrotestosterone (DHT) stops hair growth in mice by lowering a growth factor important for hair.
Platelet-rich plasma may help restore immune balance in bald patches, but its effectiveness in treating hair loss is limited.
5ARI treatment improves hair growth in older men with minimal side effects.
Finasteride microspheres help reduce hair loss for up to eight weeks with fewer side effects.
New treatment combining PRP and SVF increases hair density in 6-12 weeks for androgenetic alopecia patients.
Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.
Minoxidil is the only FDA-approved topical drug for treating male or female pattern hair loss, and other medications like finasteride and dutasteride can also increase hair growth.
Sulforaphane may help with hair growth by breaking down a hormone that causes hair loss.
Platelet-rich plasma injections significantly improved hair regrowth and thickness in patients with hair loss.
ADSC-CM treatment improved hair density and thickness in women with hair loss, safely and effectively.
Dihydrotestosterone (DHT) doesn't affect rat skin cell growth, but it does change cell cycle, protein levels, and other cell functions, potentially shortening hair growth cycle.
Using a fractional laser can stimulate hair growth, but the intensity and duration of inflammation are crucial. Too much can cause ulcers and scarring. Lower beam energy and fewer treatments are recommended to avoid damage.
PRP injections increase hair density and satisfaction in androgenetic alopecia patients.
AA-PRP injections effectively increase hair count and thickness for male pattern hair loss.
Finasteride may cause long-lasting sexual side effects.
The conclusion is that Fgf18 and Tgf-ß signaling could be targeted for hair loss treatments.
Minoxidil treats hair loss, promotes growth, has side effects, and has recent patents.
DHT affects hair follicle cells by changing microRNA levels, leading to less cell growth and more cell death.
Mice with human gene experienced hair loss when treated with DHT.
The conclusion is that accurate diagnosis of different types of hair loss requires good teamwork between skin doctors and lab experts.
Dermal cells are key in controlling hair growth and could potentially be used in hair loss treatments, but more research is needed to improve hair regeneration methods.
Chinese men have lower AGA rates than Caucasians, with type III vertex most common; family history is important.
Male pattern hair loss is genetic and influenced by hormones, with treatments like minoxidil and surgery available.
Laser/light treatments for hair loss are popular but lack scientific data proving effectiveness.
Hair loss increases with age; alcohol raises risk, more female partners lowers it.
Hair loss needs more research for better treatments.
5% minoxidil works better for hair growth and density, with minor irritation.
Hair loss from genetics and hormones can be treated with drugs or surgery.
Certain natural products may help stimulate hair growth by affecting stem cell activity in the scalp.
Male pattern baldness involves hormone-related hair thinning, shorter hair, and inflammation.