TLDR 5ARI treatment improves hair growth in older men with minimal side effects.
Several retrospective studies have examined the effectiveness of 5α-reductase inhibitors (5ARI) in treating androgenetic alopecia (AGA) in men aged 50 years or older. The studies found that 5ARI treatment with finasteride or dutasteride resulted in significant improvement in hair growth, with minimal side effects. Dutasteride showed slightly better results than finasteride, but sexual side effects may occur with the use of finasteride. Overall, the studies suggest that 5ARI treatment can be effective for hair growth in older men with AGA, but potential side effects should be considered.
6 citations,
December 2016 in “Journal of Dermatology” Dutasteride effectively and safely treats male hair loss for over a year.
13 citations,
July 2015 in “Journal of Dermatology” Finasteride effectively promotes hair growth and reduces hair loss in men with androgenetic alopecia.
35 citations,
February 2012 in “Journal of The American Academy of Dermatology” Finasteride significantly improves hair growth but may cause sexual side effects.
39 citations,
January 2012 in “Indian Dermatology Online Journal” Finasteride may cause sexual side effects like erectile dysfunction, but they are reversible and affect less than 2% of men.
44 citations,
July 2011 in “Dermatologic Therapy” Finasteride effectively increases hair growth in men with AGA, works better for those over 30, and may cause some side effects.
1 citations,
June 2021 in “Singapore Medical Journal” Dutasteride and finasteride can help increase hair growth gene expression but need further improvement.
1 citations,
April 2020 in “Journal of The American Academy of Dermatology” 5ARI treatment improves hair growth in older men with minimal side effects.
January 2018 in “Surgical and Cosmetic Dermatology” 5-alpha reductase inhibitors like finasteride and dutasteride are effective for treating enlarged prostate and male pattern hair loss.
47 citations,
January 2003 in “Current opinion in urology” A new drug, dutasteride, is at least as effective as the older drug, finasteride, for treating enlarged prostate and may have additional uses.
