Polyphenol-Rich Olive Mill Wastewater Extract and Its Potential Use in Hair Care Products

    Lisa-Marie Sittek, Thomas Schmidts, Peggy Schlupp
    Studysummary In this study, phenol-enriched olive mill wastewater extract positively influenced hair growth in vitro by promoting human dermal papilla cell proliferation, increasing insulin-like growth factor-1 secretion, and reducing reactive oxygen species, suggesting it may be beneficial for hair care.
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    Research cited in this study 39

    1. Dihydrotestosterone Inhibits Hair Growth in Mice by Inhibiting Insulin-Like Growth Factor-I Production in Dermal Papillae Growth Hormone & IGF Research · 2024
    2. Annurca Apple Polyphenols Protect Murine Hair Follicles from Taxane-Induced Dystrophy and Redirect Polyunsaturated Fatty Acid Metabolism Toward β-Oxidation Nutrients · 2018
    3. Review of Hair Follicle Dermal Papilla Cells as In Vitro Screening Model for Hair Growth International Journal of Cosmetic Science · 2018
    4. Extracellular Vesicles Derived from MSCs Activate Dermal Papilla Cells In Vitro and Promote Hair Follicle Conversion from Telogen to Anagen in Mice Scientific Reports · 2017
    5. Androgenetic Alopecia: A Review Endocrine · 2017
    6. Epigallocatechin Gallate-Mediated Alteration of the MicroRNA Expression Profile in 5α-Dihydrotestosterone-Treated Human Dermal Papilla Cells Annals of Dermatology · 2016
    7. Enhancement of Human Hair Growth Using Ecklonia Cava Polyphenols Annals of Dermatology · 2016
    8. Oxidative Stress-Associated Senescence in Dermal Papilla Cells of Men with Androgenetic Alopecia Journal of Investigative Dermatology · 2015
    9. Epidermal Stem Cells and Skin Tissue Engineering in Hair Follicle Regeneration World Journal of Stem Cells · 2015
    10. Differential Effects of Caffeine on Hair Shaft Elongation, Matrix and Outer Root Sheath Keratinocyte Proliferation, and Transforming Growth Factor-β2/Insulin-Like Growth Factor-1-Mediated Regulation of the Hair Cycle in Male and Female Human Hair Follicles In Vitro British Journal of Dermatology · 2014
    11. Caffeine’s Mechanisms of Action and Its Cosmetic Use Skin Pharmacology and Physiology · 2012
    12. Analysis of the MicroRNA Expression Profile of Normal Human Dermal Papilla Cells Treated with 5α-Dihydrotestosterone Molecular Medicine Reports · 2012
    13. Delayed Cutaneous Wound Healing and Aberrant Expression of Hair Follicle Stem Cell Markers in Mice Selectively Lacking Ctip2 in Epidermis PloS one · 2012
    14. Progress in Relevant Growth Factors Promoting the Growth of Hair Follicles American Journal of Animal and Veterinary Sciences · 2012
    15. Establishment and Characterization of an Immortalized Human Dermal Papilla Cell Line BMB Reports · 2011
    16. Dietary Isoflavone Increases Insulin-Like Growth Factor-I Production, Thereby Promoting Hair Growth in Mice The Journal of Nutritional Biochemistry · 2011
    17. Biology and Genetics of Hair Annual Review of Genomics and Human Genetics · 2010
    18. Review of Hair Follicle Dermal Cells Journal of Dermatological Science · 2009
    19. Hair Loss in Women: Comprehensive Overview and Treatment Options Seminars in Cutaneous Medicine and Surgery · 2009
    20. Effect of Caffeine and Testosterone on the Proliferation of Human Hair Follicles In Vitro International Journal of Dermatology · 2007
    21. Characteristic Features of Japanese Women's Hair With Aging and Hair Loss Journal of Dermatological Science · 2006
    22. Human Hair Growth Enhancement In Vitro By Green Tea Epigallocatechin-3-Gallate (EGCG) Phytomedicine · 2006
    23. The Hair Cycle Journal of Cell Science · 2006
    24. The Hair Growth Promoting Effect of Ascorbic Acid 2-Phosphate, a Long-Acting Vitamin C Derivative Journal of Dermatological Science · 2006
    25. Effect of 5α-Dihydrotestosterone and Testosterone on Apoptosis in Human Dermal Papilla Cells Skin Pharmacology and Physiology · 2006
    26. In Vitro Differences Between Keratinocyte Stem Cells and Transit-Amplifying Cells of the Human Hair Follicle Journal of Investigative Dermatology · 2005
    27. The Expression of Insulin-Like Growth Factor 1 in Follicular Dermal Papillae Correlates with Therapeutic Efficacy of Finasteride in Androgenetic Alopecia Journal of The American Academy of Dermatology · 2003
    28. Stress And The Hair Follicle American Journal Of Pathology · 2003
    29. Promoted Growth of Murine Hair Follicles Through Controlled Release of Vascular Endothelial Growth Factor Biomaterials · 2002
    30. Molecular Mechanisms Regulating Hair Follicle Development ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2002
    31. Control of Hair Growth and Follicle Size by VEGF-Mediated Angiogenesis Journal of Clinical Investigation · 2001
    32. In Vitro Main Pathways of Steroid Action in Cultured Hair Follicle Cells: Vascular Approach Journal of Investigative Dermatology Symposium Proceedings · 1999
    33. The Biology of Hair Follicles The New England Journal of Medicine · 1999
    34. Growth Factors and Cytokines in Hair Follicle Development and Cycling: Recent Insights from Animal Models and the Potentials for Clinical Therapy Molecular Medicine Today · 1996
    35. Growth Factors in Hair Organ Development and the Hair Growth Cycle Dermatologic Clinics · 1996
    36. Androgen Metabolism as It Affects Hair Growth in Androgenetic Alopecia Dermatologic Clinics · 1996
    37. Psychological Effects of Androgenetic Alopecia on Women: Comparisons with Balding Men and Female Control Subjects Journal of The American Academy of Dermatology · 1993
    38. Sex Hormones and Antiandrogens Influence In Vitro Growth of Dermal Papilla Cells and Outer Root Sheath Keratinocytes of Human Hair Follicles ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 1993
    39. The Psychological Effects of Androgenetic Alopecia in Men Journal of The American Academy of Dermatology · 1992

    Related research 7

    1. Possible Cellular Communication with Human Follicle Dermal Papilla Cells via Secretions from Human Hair Follicle Keratinocytes Journal of St. Marianna University · 2022
    2. A Model System to Analyze the Ability of Human Keratinocytes to Form Hair Follicles Experimental Dermatology · 2014
    3. Review of Hair Follicle Dermal Cells Journal of Dermatological Science · 2009
    4. Hair Follicle Reformation Induced by Dermal Papilla Cells from Human Scalp Skin Archives of Dermatological Research · 2006
    5. Study on Hair Follicle Formation Induced by Dermal Papilla Cells Chinese Journal of Reparative and Reconstructive Surgery · 2003
    6. Trans-Species Hair Growth Induction by Human Hair Follicle Dermal Papillae Experimental Dermatology · 2001
    7. Role of Hair Papilla Cells in Induction and Regeneration Processes of Hair Follicles Wound Repair and Regeneration · 1998