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    An Herbal Extract Combination (Biochanin A, Acetyl Tetrapeptide-3, and Ginseng Extracts) Versus 3% Minoxidil Solution for the Treatment of Androgenetic Alopecia: A 24-Week, Prospective, Randomized, Triple-Blind, Controlled Trial

    October 2020 in “ The Journal of clinical and aesthetic dermatology ”
    Suparuj Lueangarun, Ratchathorn Panchaprateep
    Studysummary In this randomized controlled study, the researchers found that an herbal extract combination showed similar efficacy to 3% minoxidil solution in treating androgenetic alopecia over 24 weeks, with no significant safety concerns, suggesting it might be a viable alternative treatment.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 28

    1. Efficacy and Safety of Oral Minoxidil 5 mg Once Daily in the Treatment of Male Patients with Androgenetic Alopecia: An Open-Label and Global Photographic Assessment Dermatology and therapy · 2020
    2. Sexual Dysfunction in Men Taking Systemic Dermatologic Medication: A Systematic Review Journal of The American Academy of Dermatology · 2019
    3. Efficacy of Topical Combination of 0.25% Finasteride and 3% Minoxidil Versus 3% Minoxidil Solution in Female Pattern Hair Loss: A Randomized, Double-Blind, Controlled Study American Journal of Clinical Dermatology · 2018
    4. Distinctive Lupus Panniculitis of Scalp with Linear Alopecia Along Blaschko's Lines: A Review of the Literature International Journal of Dermatology · 2018
    5. Evidence-Based Guideline for the Treatment of Androgenetic Alopecia in Women and Men – Short Version Journal of The European Academy of Dermatology and Venereology · 2017
    6. Effect of Miracle Fruit (Synsepalum Dulcificum) Seed Oil on the Measurable Improvement of Hair Breakage in Women with Damaged Hair: A Randomized, Double-Blind, Placebo-Controlled, Eight-Month Trial PubMed · 2017
    7. Lupus Panniculitis of the Scalp Presenting with Linear Alopecia Along the Lines of Blaschko Clinical and experimental dermatology · 2017
    8. The Effectiveness of Treatments for Androgenetic Alopecia: A Systematic Review and Meta-Analysis Journal of The American Academy of Dermatology · 2017
    9. An Open-Label Evaluator Blinded Study of the Efficacy and Safety of a New Nutritional Supplement in Androgenetic Alopecia: A Pilot Study PubMed · 2017
    10. T-Flavanone Improves Male Pattern Hair Loss by Enhancing Hair-Anchoring Strength: A Randomized, Double-Blind, Placebo-Controlled Study Dermatology and therapy · 2016
    11. A New Strategy to Modulate Alopecia Using a Combination of Two Specific and Unique Ingredients PubMed · 2013
    12. Cross-Section Trichometry: A Clinical Tool for Assessing the Progression and Treatment Response of Alopecia International journal of trichology · 2012
    13. Evidence-Based Guideline for the Treatment of Androgenetic Alopecia in Women and Men Journal der Deutschen Dermatologischen Gesellschaft · 2011
    14. Fructus Panax Ginseng Extract Promotes Hair Regeneration in C57BL/6 Mice Journal of Ethnopharmacology · 2011
    15. Medical Treatments for Male and Female Pattern Hair Loss Journal of The American Academy of Dermatology · 2008
    16. Investigation of the Topical Application of Procyanidin Oligomers from Apples to Identify Their Potential Use as a Hair-Growing Agent Journal of cosmetic dermatology · 2005
    17. A Pilot Study Evaluating the Efficacy of Topically Applied Niacin Derivatives for Treatment of Female Pattern Alopecia Journal of Cosmetic Dermatology · 2005
    18. Androgenetic Alopecia in Women Journal of Investigative Dermatology Symposium Proceedings · 2003
    19. Androgenetic Alopecia: Pathogenesis and Potential for Therapy Expert Reviews in Molecular Medicine · 2002
    20. A Randomized Clinical Trial of 5% Topical Minoxidil Versus 2% Topical Minoxidil and Placebo in the Treatment of Androgenetic Alopecia in Men Journal of The American Academy of Dermatology · 2002
    21. The Prevalence and Types of Androgenetic Alopecia in Korean Men and Women British Journal of Dermatology · 2001
    22. Investigation of Topical Application of Procyanidin B-2 from Apple to Identify Its Potential Use as a Hair Growing Agent Phytomedicine · 2000
    23. Treatment of Hair Loss The New England Journal of Medicine · 1999
    24. The Biology of Hair Follicles The New England Journal of Medicine · 1999
    25. Finasteride in the Treatment of Men with Androgenetic Alopecia Journal of The American Academy of Dermatology · 1998
    26. Diagnostic and Predictive Value of Horizontal Sections of Scalp Biopsy Specimens in Male Pattern Androgenetic Alopecia Journal of The American Academy of Dermatology · 1993
    27. Human Hair Growth In Vitro Journal of Cell Science · 1990
    28. Classification of the Types of Androgenetic Alopecia (Common Baldness) Occurring in the Female Sex British Journal of Dermatology · 1977

    Related research 20

    1. Sublingual Minoxidil for the Treatment of Male and Female Pattern Hair Loss: A Randomized, Double-Blind, Placebo-Controlled, Phase 1B Clinical Trial Journal of The European Academy of Dermatology and Venereology · 2021
    2. SULT1A1 (Minoxidil Sulfotransferase) Enzyme Booster Significantly Improves Response to Topical Minoxidil for Hair Regrowth Journal of Cosmetic Dermatology · 2021
    3. Comparison of 5% Minoxidil Lotion Monotherapy Versus Its Combination with Autologous Platelet-Rich Plasma in Androgenetic Alopecia in One Hundred Males Medical journal, Armed Forces India · 2021
    4. Comparative Study of Efficacy of Minoxidil Versus Minoxidil with Platelet-Rich Plasma Versus Minoxidil with Dermaroller in Androgenetic Alopecia International Journal of Research in Dermatology · 2021
    5. Efficacy and Safety of a Novel Herbal Solution for the Treatment of Androgenetic Alopecia and Comparison with 5% Minoxidil: A Double-Blind, Randomized Controlled Trial Study Dermatologic Therapy · 2020
    6. Evaluation of the Efficacy and Safety of Cow Placenta Extract Lotion Versus Minoxidil 2% in the Treatment of Female Pattern Androgenetic Alopecia International Journal of Women's Dermatology · 2020
    7. Comparison of Efficacy of Platelet-Rich Plasma Therapy With or Without Topical 5% Minoxidil in Male-Type Baldness: A Randomized, Double-Blind Placebo Control Trial Indian Journal of Dermatology, Venereology and Leprology · 2019
    8. A Randomized Controlled, Single-Observer Blinded Study to Determine the Efficacy of Topical Minoxidil Plus Microneedling Versus Topical Minoxidil Alone in the Treatment of Androgenetic Alopecia Journal of Cutaneous and Aesthetic Surgery · 2018
    9. The Clinical Effect of JetPeel-Assisted Topical Minoxidil in the Treatment of Androgenetic Alopecia: A Randomized Pilot Study Journal of Cosmetic and Laser Therapy · 2017
    10. Combined Treatment with Oral Finasteride and Topical Minoxidil in Male Androgenetic Alopecia: A Randomized and Comparative Study in Chinese Patients Dermatologic Therapy · 2015
    11. Comparing the Effectiveness of Local Solution of Minoxidil and Caffeine 2.5% with Local Solution of Minoxidil 2.5% in Treatment of Androgenetic Alopecia Journal of Mazandaran University of Medical Sciences · 2013
    12. Preparation and Evaluation of a Multimodal Minoxidil Microemulsion Versus Minoxidil Alone in the Treatment of Androgenic Alopecia of Mixed Etiology: A Pilot Study Drug Design Development and Therapy · 2013
    13. A Multicenter, Randomized, Placebo-Controlled, Double-Blind Clinical Trial of a Novel Formulation of 5% Minoxidil Topical Foam Versus Placebo in the Treatment of Androgenetic Alopecia in Men Journal of The American Academy of Dermatology · 2007
    14. Multicenter Double Blind Randomized Placebo Controlled Clinical Trial of Minoxidil Gel in the Treatment of Alopecia Areata The Chinese Journal of Clinical Pharmacology · 2006
    15. A Randomized, Placebo-Controlled Trial of 5% and 2% Topical Minoxidil Solutions in the Treatment of Female Pattern Hair Loss Journal of The American Academy of Dermatology · 2004
    16. A Randomized Clinical Trial of 5% Topical Minoxidil Versus 2% Topical Minoxidil and Placebo in the Treatment of Androgenetic Alopecia in Men Journal of The American Academy of Dermatology · 2002
    17. Comparative Efficacy of Various Treatment Regimens for Androgenetic Alopecia in Men Journal of Dermatology · 2002
    18. Changes in Hair Weight and Hair Count in Men with Androgenetic Alopecia After Application of 5% and 2% Topical Minoxidil, Placebo, or No Treatment Journal of The American Academy of Dermatology · 1999
    19. Treatment of Male Pattern Alopecia Using Topical Minoxidil in The Netherlands International Journal of Dermatology · 1988
    20. Androgenetic Alopecia Treated With Topical Minoxidil Journal of The American Academy of Dermatology · 1987