Investigation of Topical Application of Procyanidin B-2 from Apple to Identify Its Potential Use as a Hair Growing Agent

December 2000 in “ Phytomedicine ”

Ayako Kamimura, Tomoya Takahashi, Yasusi Watanabe

procyanidin B-2 hair growth agent male pattern baldness placebo terminal hairs apple extract

TLDR Apple-derived procyanidin B-2 can safely promote hair growth in men.

In a study from 2000, 29 male subjects were involved in a double-blind clinical trial to test the effectiveness of procyanidin B-2, a compound from apples, as a hair growth agent. The trial lasted 6 months, with 19 subjects using procyanidin B-2 and 10 using a placebo. The results indicated a significant increase in the number of total hairs and terminal hairs for the procyanidin B-2 group compared to the placebo group, with no adverse side effects reported. The study concluded that procyanidin B-2 is a safe and promising treatment for male pattern baldness.

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