Procyanidin B-2
Research
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research Procyanidin B-2 Extracted from Apples Promotes Hair Growth: A Laboratory Study
This study found that procyanidin B-2 may promote hair growth by reducing expression and inhibiting translocation of PKC isozymes in murine hair epithelial cells.
research Investigation of Topical Application of Procyanidin B-2 from Apple to Identify Its Potential Use as a Hair Growing Agent
In this study, 1% procyanidin B-2 tonic significantly increased the number of total and terminal hairs on the scalp of male participants compared to a placebo after 6 months of use.
research Toxicological Studies on Procyanidin B-2 for External Application as a Hair Growing Agent
This study suggests that topical procyanidin B-2 is safe for use as a hair growth agent, as it showed no mutagenic effects or significant irritation in a series of toxicological tests.
research The First Clinical Trial of Topical Application of Procyanidin B-2 to Investigate Its Potential as a Hair Growing Agent
This study reported that a 1% procyanidin B-2 tonic increased hair diameter and density in men with male pattern baldness, suggesting it may be a potential treatment option.
research Procyanidin B-2 and the Hair-Growing Activity of Proanthocyanidins
This study found that purified apple juice containing procyanidin B-2 promoted hair growth in both mouse models and human clinical trials for male pattern baldness.
research Evaluation of the Efficacy and Safety of Topical Procyanidin B2 and Placebo in the Treatment of Androgenetic Alopecia in Men: A Randomized, Double-Blind, Placebo-Controlled Study
This placebo-controlled study found that topical procyanidin B2 significantly increased total and anagen hair counts in men with androgenetic alopecia over 16 weeks compared to placebo, suggesting it as an effective and safe treatment option.
research Procyanidins Attenuate Neuropathic Pain by Suppressing Matrix Metalloproteinase-9/2
This study found that procyanidins effectively alleviate neuropathic pain in mice by significantly inhibiting MMP-9/2 activity.
research Studies on a Hair Growth Stimulant, Procyanidin B-2
research Early Plant Growth and Biochemical Responses Induced by Azospirillum Brasilense Sp245 Lipopolysaccharides in Wheat (Triticum Aestivum L.) Seedlings Are Attenuated by Procyanidin B2
In this laboratory study, procyanidin B2 inhibited early plant growth and biochemical responses in wheat seedlings treated with lipopolysaccharides from Azospirillum brasilense, suggesting that plant response activation requires LPS recognition by plant cells.
research Procyanidin Oligomers Selectively and Intensively Promote Proliferation of Mouse Hair Epithelial Cells In Vitro and Activate Hair Follicle Growth In Vivo
This study found that procyanidin oligomers, particularly dimers and trimers, significantly promoted hair growth in mice and hair epithelial cell cultures, suggesting potential use as hair growth agents.
research Several Selective Protein Kinase C Inhibitors Including Procyanidins Promote Hair Growth
In this study, procyanidin B-2 and C-1 were found to promote hair growth by selectively inhibiting protein kinase C, supporting their potential use for hair-growing activity.
research Procyanidin Oligomers Counteract TGF-β1- and TGF-β2-Induced Apoptosis in Hair Epithelial Cells: An Insight into Their Mechanisms
This study found that procyanidin oligomers from apples and barley may stimulate hair growth by promoting hair epithelial cell proliferation and protecting them from apoptosis via MEK activation in a murine model.
research African Baobab (Adansonia Digitata) Fruit as a Promising Source of Procyanidins
This study provides a detailed profile of bioactive polyphenols in various parts of the baobab fruit, highlighting its potential as a health-promoting food or supplement.
research Therapeutic Strategies for Treating Hair Loss
This article discusses the need for rational strategies in developing hair loss drugs targeting specific events in hair follicle cycling, reporting no clinical findings but emphasizing the importance of understanding molecular controls.
research Complementary and Alternative Treatments for Alopecia: A Comprehensive Review
This review examines complementary and alternative medicine for alopecia and finds limited support from robust clinical trials, highlighting the need for standardized studies to evaluate efficacy and safety.
research Polyphenols from the Heartwood of Cercidiphyllum Japonicum and Their Effects on Proliferation of Mouse Hair Epithelial Cells
In this study, the methanol extract of Cercidiphyllum japonicum heartwood was found to stimulate the proliferation of mouse hair epithelial cells, with several isolated compounds showing significant proliferative activities.
research Can Plant-Derived Phytochemicals Provide Symptom Relief for Hair Loss? A Critical Review
This review discusses the potential benefits of phytochemicals for hair care and emphasizes the need for more robust preclinical and clinical studies, without reporting new clinical results.
research Annurca Apple Extract - A Breakthrough in Alopecia Phytotherapy: A Literature Review
This review suggests that annurca apple extract, rich in polyphenols, may be a promising alternative for treating baldness, though further research is needed to clearly assess its effectiveness compared to existing treatments.
research Hair Loss
Some alternative treatments may help with hair loss, but more evidence is needed to confirm their effectiveness.
research Cosmeceuticals for Hair Loss and Hair Care
This review discusses potential cosmeceutical treatments for hair loss, including ingredients like procyanidins and isoflavones, but does not present new clinical outcomes; the authors highlight the promise of further research.