Toxicological Studies on Procyanidin B-2 for External Application as a Hair Growing Agent

    May 1999 in “ Food and chemical toxicology ”
    Tomoya Takahashi, Yoshiharu Yokoo, Takatoshi Inoue, Akira Ishii
    Studysummary This study suggests that topical procyanidin B-2 is safe for use as a hair growth agent, as it showed no mutagenic effects or significant irritation in a series of toxicological tests.
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    Research cited in this study 2

    1. Procyanidin Oligomers Selectively and Intensively Promote Proliferation of Mouse Hair Epithelial Cells In Vitro and Activate Hair Follicle Growth In Vivo ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 1999
    2. Proanthocyanidins from Grape Seeds Promote Proliferation of Mouse Hair Follicle Cells In Vitro and Convert Hair Cycle In Vivo Acta dermato-venereologica · 1998