TLDR Procyanidin B-2 from apple juice significantly increases hair growth and may be more effective than minoxidil without side effects.
The document from 2001 detailed a study on the effects of procyanidin B-2, a compound from apple juice, on hair growth, particularly as a treatment for male pattern baldness. In vitro tests showed over a 300% increase in hair epithelial cell growth compared to controls. In vivo tests on mice and a 6-month clinical trial with 19 men revealed that a 1% procyanidin B-2 topical solution significantly increased the number of total hairs, with marked hair-growing activity and no toxicological issues. The study concluded that procyanidin B-2 is a potent hair growth stimulant, potentially more effective than minoxidil, without adverse side effects.
37 citations,
May 1999 in “Australasian Journal of Dermatology” Early diagnosis and treatment are crucial for preventing permanent hair loss in various scalp conditions, and while new treatments are promising, more research is needed to evaluate their effectiveness.
79 citations,
March 1999 in “The journal of investigative dermatology/Journal of investigative dermatology” Procyanidin compounds from grape seeds were found to significantly increase mouse hair growth.
64 citations,
October 1998 in “Acta dermato-venereologica” Grape seed proanthocyanidins can promote hair growth.
53 citations,
March 1987 in “Journal of The American Academy of Dermatology” Minoxidil effectively regrows hair in male pattern baldness.
39 citations,
March 1987 in “Journal of The American Academy of Dermatology” Topical minoxidil is a safe and effective treatment for hair loss caused by androgenetic alopecia.
44 citations,
March 1987 in “Journal of The American Academy of Dermatology” Using minoxidil on balding scalps can stimulate hair regrowth and increase blood flow. It's an effective treatment for early hair loss.
46 citations,
February 1983 in “The Journal of Dermatology” Hair regrowth slows with age due to changes in enzyme activity.
