Procyanidin B-2 and the Hair-Growing Activity of Proanthocyanidins

    January 2001 in “ Cosmetics and toiletries
    Tomoya Takahashi, Ayako Kamimura, Yoshiharu Yokoo, Yasusi Watanabe, Brian M. Lawrence
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    TLDR Procyanidin B-2 from apple juice significantly increases hair growth and may be more effective than minoxidil without side effects.
    The document from 2001 detailed a study on the effects of procyanidin B-2, a compound from apple juice, on hair growth, particularly as a treatment for male pattern baldness. In vitro tests showed over a 300% increase in hair epithelial cell growth compared to controls. In vivo tests on mice and a 6-month clinical trial with 19 men revealed that a 1% procyanidin B-2 topical solution significantly increased the number of total hairs, with marked hair-growing activity and no toxicological issues. The study concluded that procyanidin B-2 is a potent hair growth stimulant, potentially more effective than minoxidil, without adverse side effects.
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