Distinctive Lupus Panniculitis of Scalp with Linear Alopecia Along Blaschko's Lines: A Review of the Literature

Lupus panniculitis of the scalp (LPS) was a rare manifestation of lupus erythematosus panniculitis (LEP) characterized by linear alopecia along Blaschko's lines. A review of 20 cases (mean age 26.4 years, equal gender ratio) revealed that the parietal region was most commonly affected (70%), followed by frontal (45%), temporal (40%), occipital (30%), and vertex (10%) areas. Lesions were typically linear, annular, arch-shaped, or ulcerative. Antinuclear antibodies (ANA) were present in 60% of cases. Treatments such as hydroxychloroquine, oral prednisolone, intralesional corticosteroid, and methotrexate led to complete response within an average of 8.08 weeks. Systemic lupus erythematosus (SLE) developed in 20% of cases, with a recurrence rate of 35%. Continuous follow-up was recommended to prevent recurrence and SLE development.