Lupus Panniculitis Clinically Simulating Alopecia Areata

In 2002, a case study reported a patient with a history of lupus erythematosus who developed non-scarring alopecia, initially suspected to be alopecia areata. However, clinical examination and a scalp biopsy indicated the presence of lupus panniculitis. The biopsy showed lymphocytic inflammation around the deep segments of hair follicles and bulbs, hyalinization of fat, and mucinosis in the subcutaneous tissue. Treatment with topical corticosteroids, sun protection, and hydroxychloroquine led to the resolution of the skin lesions and alopecia. This case emphasized the need for accurate diagnosis between lupus panniculitis, alopecia areata, and discoid lupus erythematosus using clinical and histological analysis.