A Case of Linear Alopecia of the Scalp
January 2020
in “
Skin Appendage Disorders
”
linear alopecia scalp lupus panniculitis chronic cutaneous lupus erythematosus erythematous-violaceous plaque follicular units lobular panniculitis lymphohistiocytic infiltrate methotrexate prednisolone non-scarring alopecia Blaschko's lines hair loss lupus skin plaque hair follicles skin inflammation immune cells steroid
TLDR Treatment with methotrexate and prednisolone led to complete hair regrowth and no relapse for 2 years.
A 14-year-old male presented with a 1-year history of linear hair loss on the scalp, diagnosed as lupus panniculitis of the scalp (LPS)-associated chronic cutaneous lupus erythematosus. Clinical and histopathological findings included erythematous-violaceous plaque, follicular units with single hairs, and lobular panniculitis with lymphohistiocytic infiltrate. Treatment with methotrexate and prednisolone led to complete hair regrowth and resolution of facial lesions within 4 months. The patient remained relapse-free for 2 years post-treatment. LPS is characterized by non-scarring alopecia, rapid treatment response, and a distinct pattern along Blaschko's lines.
