August 2026 in “Prostaglandins & Other Lipid Mediators” This review suggests that imbalance in prostaglandin levels may contribute to androgenetic alopecia, highlighting prostaglandins as potential biomarkers and therapeutic targets for the condition.
April 2023 in “Russian Journal of Clinical Dermatology and Venereology” This study found that after a 4-month comprehensive therapy course, 90.5% of patients with androgenetic alopecia and telogen effluvium showed hair condition improvement, highlighting the potential benefits of adjuvant proteoglycan replacement therapy in these conditions.
5 citations
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May 2023 in “European Journal of Human Genetics” This study found that mutations in the TULP3 gene are associated with progressive degeneration of the liver, kidney, and heart in adults, highlighting the importance of early detection and management.
3 citations
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June 2017 in “Medical lasers” In this case report, hair graying improved in a patient with male pattern hair loss after combined treatment with thulium laser energy and polydeoxyribonucleotide injections, suggesting potential therapeutic benefits.
18 citations
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August 2012 in “Chinese journal of integrative medicine/Chinese Journal of Integrative Medicine” This study reported that total glucosides of paeony capsules were as effective and safe as compound glycyrrhizin tablets for treating mild to moderate alopecia areata.
November 2012 in “The Journal of Urology” Certain gene variants may raise the risk of prostate enlargement, but taking NSAIDs could reduce this risk.
May 2005 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” In this study, transgenic mice with a truncated latent transforming growth factor-beta-binding protein showed reduced keratinocyte proliferation and alterations in the hair cycle due to mis-localization of transforming growth factor-beta.
5 citations
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June 2012 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that applying topical thymidine dinucleotide (pTT) to newborn mice before UV exposure delayed and reduced melanoma development compared to untreated controls.
18 citations
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October 2021 in “Frontiers in Physiology” This review summarizes recent research on the molecular properties and functions of L-PGDS and PGD2, but reports no new findings, highlighting their pathophysiological roles and guiding future studies.
This article explores the potential applications of polyglutamic acid in cosmetics, discussing its benefits for skincare and haircare, but reports no new experimental results.
32 citations
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January 2000 in “International Journal of Cancer” In this study, the researchers observed significant down-regulation of Transglutaminase-3 expression in esophageal cancer tissues compared to normal tissues, suggesting its alteration is a common event in esophageal cancer development.
June 2025 in “Dermatologic Surgery” This study found that growth factor concentrate provides quicker improvements for patterned hair loss, but platelet-rich plasma offers more sustained benefits after treatment.
16 citations
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September 2016 in “Neuropharmacology” This study suggests that in an ex vivo rat glaucoma model, TSPO activation is involved in Allopregnanolone synthesis and may help prevent retinal damage, with TSPO agonists as potential therapeutic agents.
August 2025 in “Intisari Sains Medis” This study found that in healthy individuals, TGF-β1 levels in platelet-rich plasma are significantly higher when extracted using the buffy coat method compared to the pure method, with additional gender differences observed only in the buffy coat PRP.
43 citations
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January 2016 in “Oxidative medicine and cellular longevity” This review discusses the biological effects and mechanisms of THSG in antiaging and related disease treatments but reports no new experimental findings.
18 citations
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February 2018 in “International Journal of Molecular Sciences” This study found that prostaglandin D2 promotes androgen receptor and AKT signaling in human dermal papilla cells through the DP2 receptor, potentially contributing to androgenetic alopecia.
April 2019 in “Journal of Investigative Dermatology” The study suggests that variability in platelet-derived growth factors in PRP is influenced by both patient-to-patient differences and the devices used for PRP preparation, contributing to inconsistent clinical outcomes in hair loss treatments.
May 2005 in “Molecular Carcinogenesis” This study found that mrp/plf-mRNA expression in murine skin increases in response to different tumor promoters, suggesting its potential as a short-term biomarker for chemical carcinogenesis.
16 citations
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February 2018 in “BMC Genomics” This paper reviews genome-based personalized medicine developments using Web services for analyzing SNPs in reproductive potential but reports no new clinical findings.
April 2018 in “The Journal of Urology” This study found that phosphodiesterase inhibitors may suppress the proliferation of benign prostatic hyperplasia epithelial cells by modulating CCL5 levels in low androgen conditions.
2 citations
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September 2016 in “Journal of Dermatological Science” Reduced TRPS1 leads to increased STAT3 and SOX9 in hair follicles, affecting hair growth.
July 2024 in “Journal of Investigative Dermatology” Recombinant human TSG-6 speeds up wound healing in diabetic mice.
November 1968 in “Journal of the American Pharmaceutical Association”
This study found that PRP injections may safely improve penile curvature and PDQ scores in men with stable-phase Peyronie's Disease, although the curvature reduction observed was not enough to determine long-term clinical significance.
1 citations
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August 2025 in “Bioengineering” In this study, the combination of full-thickness skin column grafts and the TSN6 peptide improved wound healing quality in pigs by enhancing epidermal maturation compared to other treatments.
February 2026 in “Optics” This study demonstrates that polarized second harmonic generation imaging effectively monitors wool fiber stretching, revealing significant structural changes in keratin alignment that improve textile performance.
PTHrP is important for bone formation and may be targeted for osteoporosis treatment and longevity therapies.
January 2022 in “Research Square (Research Square)” This study found that elevated TSPEAR expression in colorectal cancer was associated with poor overall prognosis and correlated with tumor infiltrating immune cells, suggesting its potential as a predictive biomarker.
3 citations
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January 2018 in “International Journal of Trichology” The authors concluded that their new grading system can effectively classify early female pattern hair loss and evaluate treatment progress.
January 2021 in “TURKISH JOURNAL OF VETERINARY AND ANIMAL SCIENCES” In this study, PRP administration in rabbit tibia bones with segmental defects improved bone healing scores and advanced bone development stages compared to the control group.