Patient and Device Generated Variability in Platelet-Derived Growth Factors During Platelet-Rich Plasma Therapy for Hair Loss

    April 2019 in “ Journal of Investigative Dermatology ”
    Maria K. Hordinsky, N. Estharabadi, Raymond Farah, J. Mohammed
    Image of study
    TLDR Differences in growth factors in platelet-rich plasma therapy for hair loss can vary between patients and can be influenced by the devices used, possibly leading to inconsistent results.
    In 2019, a study involving 34 volunteers investigated the variability in platelet-derived growth factors during platelet-rich plasma (PRP) therapy for hair loss. The research used two different FDA-cleared devices to prepare PRP. The findings revealed significant variability in the expression and levels of growth factors in PRP between patients, particularly for VEGF and EGF, with the least variability for TGFB1. The study also found individual differences in growth factor levels when comparing PRP prepared from both devices. The conclusion was that these differences in growth factors could be inherent between patients and could also be influenced by the devices used to prepare PRP, potentially leading to inconsistent clinical responses.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 87 results

      community New and Interesting HairLoss Studies/Papers/Reviews

      in Treatment  41 upvotes 5 years ago
      Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.
      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      in Research  830 upvotes 7 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community I cry every day, everything is very depressing

      in Finasteride/Dutasteride  52 upvotes 1 week ago
      A user is experiencing hair loss despite using dutasteride and oral minoxidil, feeling hopeless and considering a hair system. They are advised to try ketoconazole, seek a second opinion from a dermatologist, and consider treatments like finasteride, RU58841, and hair transplants.

      community Do Platelet-rich plasma, PRP work?

      in Research/Science  12 upvotes 1 year ago
      Someone's brother tried Platelet-rich plasma (PRP) for hair loss; it had minimal effect on hair but improved skin appearance. Microneedling at home was suggested as a more sustainable alternative.

      community PRP ( PLATELET-RICH-PlASMA) for hair loss

      in Treatment  1 upvotes 1 year ago
      A 27-year-old male experiencing hair loss post-Covid is considering PRP (platelet-rich plasma) therapy. He's seeking personal experiences about the process, particularly regarding pain levels, despite his dermatologist's assurance of using local anesthesia.

    Related Research

    1 / 1 results