Investigation of the Comprehensive Treatment’s Clinical Efficacy of Various Types of Alopecia Using Proteoglycan Replacement Therapy

    April 2023 in “ Russian Journal of Clinical Dermatology and Venereology ”
    Aida Gadzhigoroeva, Yu. Yu. Romanova, В В Вавилов, Yu.A. Markova
    Studysummary This study found that after a 4-month comprehensive therapy course, 90.5% of patients with androgenetic alopecia and telogen effluvium showed hair condition improvement, highlighting the potential benefits of adjuvant proteoglycan replacement therapy in these conditions.
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    Research cited in this study 7

    1. Integral Roles of Specific Proteoglycans in Hair Growth and Hair Loss: Mechanisms Behind the Bioactivity of Proteoglycan Replacement Therapy with Nourkrin with Marilex in Pattern Hair Loss and Telogen Effluvium Dermatology Research and Practice · 2020
    2. Isolation and Quantification of Glycosaminoglycans from Human Hair Shaft Annals of Dermatology · 2016
    3. The Androgen Receptor Antagonizes Wnt/β-Catenin Signaling in Epidermal Stem Cells Journal of Investigative Dermatology · 2015
    4. A Newly Discovered Linkage Between Proteoglycans and Hair Biology: Decorin Acts as an Anagen Inducer Experimental Dermatology · 2014
    5. Hair Cycle-Specific Expression of Versican in Human Hair Follicles Journal of Dermatological Science · 2005
    6. Molecular Control of Epithelial-Mesenchymal Interactions During Hair Follicle Cycling ˜The œjournal of investigative dermatology. Symposium proceedings/˜The œJournal of investigative dermatology symposium proceedings · 2003
    7. Differences in Hair Follicle Dermal Papilla Volume Are Due to Extracellular Matrix Volume and Cell Number: Implications for the Control of Hair Follicle Size and Androgen Responses Journal of Investigative Dermatology · 1999