The Use of Therapeutic Peptides in Combination With Full-Thickness Skin Columns to Improve Healing of Excisional Wounds

    August 2025 in “ Bioengineering ”
    Anders H. Carlsson, Ira M. Herman, Sean Christy … Kristo Nuutila
    Studysummary In this study, the combination of full-thickness skin column grafts and the TSN6 peptide improved wound healing quality in pigs by enhancing epidermal maturation compared to other treatments.
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    Research cited in this study 4

    1. A Matrix-Derived Bioactive Peptide Enhances Epidermal Thickness and Hair Follicle Neogenesis in Grafted Dermal-Epidermal Composites Wound Repair and Regeneration · 2025
    2. Wound-Induced Hair Follicle Neogenesis as a Promising Approach for Hair Regeneration Molecules and Cells · 2023
    3. Multi-Faceted Enhancement of Full-Thickness Skin Wound Healing by Treatment with Autologous Micro Skin Tissue Columns Scientific Reports · 2021
    4. Reconstitution of Full-Thickness Skin by Microcolumn Grafting Journal of Tissue Engineering and Regenerative Medicine · 2016