research Insulin Resistance and Elevated Androgen Levels: A Major Cause of Polycystic Ovary Syndrome
Insulin resistance and high male hormone levels are major causes of Polycystic Ovary Syndrome.
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research A Systematic Summary of Survival and Death Signaling During the Life of Hair Follicle Stem Cells
The conclusion is that understanding how hair follicle stem cells live or die is important for maintaining healthy tissue and repairing injuries, and could help treat hair loss, but there are still challenges to overcome.
research Rare and Common Genetic Determinants of Metabolic Individuality and Their Effects on Human Health
Genetic variations greatly affect individual metabolism and can impact health and disease risk.
research Platelet-Derived Bio-Products: Classification Update, Applications, Concerns, and New Perspectives
Platelet-derived bio-products help in wound healing and tissue regeneration but lack standardized methods, and their use in medicine is growing.
research Overview of Urethral Reconstruction by Tissue Engineering: Current Strategies, Clinical Status, and Future Direction
The best method for urethral reconstruction is using hypoxia-preconditioned stem cells with autologous cells on a vascularized synthetic scaffold.
research MSCs and Their Exosomes: A Rapidly Evolving Approach in the Context of Cutaneous Wound Therapy
MSCs and their exosomes may speed up skin wound healing but need more research for consistent use.
research Extracellular Vesicles from Hair Follicle-Derived Mesenchymal Stromal Cells: Isolation, Characterization, and Therapeutic Potential for Chronic Wound Healing
Hair follicle-derived extracellular vesicles may help heal chronic wounds as effectively as those from adipose tissue.
research Scaffold-Based Developmental Tissue Engineering Strategies for Ectodermal Organ Regeneration
Scaffold-based strategies show promise for regenerating hair follicles and teeth but need more research for clinical use.
research Engineered Hair Follicle Mesenchymal Stem Cells Overexpressing Controlled-Release Insulin Reverse Hyperglycemia in Mice with Type 1 Diabetes
Genetically modified stem cells from human hair follicles can lower blood sugar and increase survival in diabetic mice.
research Establishment of an Efficient Primary Culture System for Human Hair Follicle Stem Cells Using the Rho-Associated Protein Kinase Inhibitor Y-27632
A new method using Y-27632 improves the growth and quality of human hair follicle stem cells for tissue engineering and therapy.
research Therapeutic Effects of Stem Cells in Different Body Systems: A Comprehensive Review
Stem cell therapy is promising for treating various health conditions, but more research is needed to understand its full potential and address challenges.
research Mesenchymal Stem Cells Antagonize IFN-Induced Proinflammatory Changes and Growth Inhibition Effects via Wnt/β-Catenin and JAK/STAT Pathway in Human Outer Root Sheath Cells and Hair Follicles
Mesenchymal stem cells may help treat hair loss by improving hair cell growth and reducing inflammation.
research Laminin-511, Inducer of Hair Growth, Is Down-Regulated and Its Suppressor in Hair Growth, Laminin-332 Up-Regulated in Chemotherapy-Induced Alopecia
Chemotherapy-induced hair loss is partly due to decreased laminin-511 and increased laminin-332.
research Identification and Characterization of Four Immune-Related Signatures in Keloid
Four specific genes are linked to keloid formation and could be potential treatment targets.
research Hair Follicle-Derived Mesenchymal Stem Cells Decrease Alopecia Areata Mouse Hair Loss and Reduce Inflammation Around the Hair Follicle
Hair follicle stem cells reduced hair loss and inflammation in mice with a condition similar to human alopecia.
research The Roles of Non-Coding RNA in the Development and Regeneration of Hair Follicles: Current Status and Further Perspectives
Non-coding RNAs are important for hair growth and could lead to new hair loss treatments, but more research is needed.
research Biofabrication of Human Skin with Its Appendages
Current methods can't fully recreate skin and its features, and more research is needed for clinical use.
research Update on Melasma—Part I: Pathogenesis
Melasma's causes include genetics, sun exposure, hormones, and oxidative stress, and understanding these can help create better treatments.
research Effects of Periplaneta Americana Extracts on the Growth and Proliferation of Cutaneous Interstitial Cells in Cutaneous-Wound Healing
Kangfuxin (KFX) extract speeds up wound healing and improves skin regeneration.
research Editorial: Mesenchymal Stromal Cell Therapy for Regenerative Medicine
Mesenchymal stromal cell therapies show promise for treating various diseases but need more research and standardization.
research Regenerative Medicine Strategies for Hair Growth and Regeneration: A Narrative Review of Literature
New regenerative treatments for hair loss show promise but need more research for confirmation.
research Self-Amplifying RNA Approach for Protein Replacement Therapy
Self-amplifying RNA could be a better option for protein replacement therapy with lower doses and lasting effects, but delivering it into cells is still challenging.
research Extracellular Vesicles in Facial Aesthetics: A Review
Tiny particles called extracellular vesicles show promise for skin improvement and anti-aging in facial care but face challenges like low production and lack of research.
research Putting the Human Hair Follicle Cycle on the Map
The research created a model to understand human hair growth cycle, which can help diagnose and treat hair growth disorders and test potential hair growth drugs.
research Therapeutic Values of Exosomes in Cosmetics, Skin Care, Tissue Regeneration, and Dermatological Diseases
Exosomes could be effective for improving skin health and treating skin diseases.
research Dual-Action Icariin-Containing Thermosensitive Hydrogel for Wound Macrophage Polarization and Hair Follicle Neogenesis
The gel with icariin speeds up wound healing, reduces scarring, and helps hair growth by controlling BMP4 signaling. It also reduces inflammation and improves wound quality in mice, adapts to different wound shapes, and gradually releases icariin to aid healing. It also prevents too much collagen and myofibroblast formation during skin healing.
research Exosomes Secreted from Adipose-Derived Stem Cells Are a Potential Treatment Agent for Immune-Mediated Alopecia
Exosomes from fat-derived stem cells can potentially improve hair growth and could be a new treatment for immune-related hair loss.
research The Effects of Lower vs Higher Cell Number of Platelet-Rich Plasma on Hair Density and Diameter in Androgenetic Alopecia: A Randomized, Double-Blinded, Placebo, Parallel-Group Half-Scalp IRB-Approved Study
Higher cell number PRP improves hair density and diameter more than lower cell number PRP.
research Comparative Characterization and Osteogenic/Adipogenic Differentiation of Mesenchymal Stem Cells Derived from Male Rat Hair Follicles and Bone Marrow
Hair follicle stem cells are similar to bone marrow stem cells but are better for fat cell research.
research Skipping of Exons by Premature Termination of Transcription and Alternative Splicing Within Intron-5 of the Sheep SCF Gene: A Novel Splice Variant
A new mRNA variant of the SCF gene in sheep skin produces a shorter, different protein.