Engineered Hair Follicle Mesenchymal Stem Cells Overexpressing Controlled-Release Insulin Reverse Hyperglycemia in Mice with Type 1 Diabetes

    May 2014 in “ Cell transplantation ”
    Chunling Wu, Feilin Liu, Pengdong Li … Jin Yu Liu
    Studysummary This study demonstrated that genetically engineered stem cells from human hair follicles can reverse hyperglycemia and reduce mortality in mice with type 1 diabetes by overexpressing the human insulin gene.
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    Research cited in this study 2

    1. Maintenance of High Proliferation and Multipotent Potential of Human Hair Follicle-Derived Mesenchymal Stem Cells by Growth Factors International Journal of Molecular Medicine · 2013
    2. Cultured Cells From the Adult Human Hair Follicle Dermis Can Be Directed Toward Adipogenic and Osteogenic Differentiation Journal of Investigative Dermatology · 2005

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    1. Trans-Species Hair Growth Induction by Human Hair Follicle Dermal Papillae Experimental Dermatology · 2001