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In a murine model of androgenetic alopecia, this study found that the newly designed IGF-1 biomimetic peptide Ac-GFFY-IGF led to faster and superior hair regrowth compared to minoxidil, suggesting potential for improved human therapies.

This study found that vitamin D supplementation in diets of Rex rabbits improved hair follicle development and fatty acid metabolism, with 1400–2100 IU/kg proving most effective for hair density and 2800 IU/kg increasing hair length.

This study investigated the genetic factors influencing cashmere quality differences between Jiangnan cashmere goats and Changthangi pashmina goats, identifying 4,942 differentially expressed genes and highlighting 24 key genes related to hair follicle development and cashmere fiber formation.

In this study, Rosa rugosa water extract improved hair length and thickness in a mouse model of DHT-induced alopecia by enhancing the expression of hair growth-promoting factors while inhibiting growth-suppressive proteins, suggesting its potential as a natural therapy for hair loss prevention.

This study observed that IGF-1R expression significantly decreased in basal keratinocytes of sacrococcygeal pilonidal sinus tissues, suggesting a potential role in its etiology, although further data are needed to evaluate its treatment implications.

In this study, autologous platelet-rich plasma improved skin wound healing in mice, associated with reduced inflammation and enhanced angiogenesis and re-epithelialization, but the underlying regulatory mechanism requires further investigation.

This review discusses the effects of IGF-1 on hair follicle cell proliferation and differentiation, highlighting its roles in paracrine signaling, apoptosis prevention, and hair growth, but reports no new clinical results.

This study highlights the evolving understanding of acne's pathophysiology and suggests that targeting pro-inflammatory cytokines such as IL-1β, IL-17, IL-23, and TNFα with biological antibodies may offer new treatment strategies for severe acne and its scars.

This review discusses hormonal influences on hair growth and suggests that understanding hormone-gene interactions may improve treatment of hirsutism and alopecia, but reports no new clinical findings.

This study found that IGF1, retinoic acid, and dexamethasone increase IGFBP-3 production in cultured human dermal papilla cells, potentially inhibiting IGF1 action on hair growth.

In this study, researchers found that overexpression of IGF-1 in transgenic mice stimulated increased vibrissa growth during the first neonatal hair cycle compared to their nontransgenic littermates.

In this study, DHT was found to inhibit hair growth in mice by decreasing IGF-I production in dermal papillae through reduced sensory neuron stimulation.

This study suggests that M2 macrophages play a key role in promoting wound-induced hair neogenesis in mice by producing growth factors like Igf1 and Fgf2.

This study found that local androgen biosynthesis and metabolism in human sebaceous glands play a crucial role in sebum synthesis and secretion.

This study suggests that icariin promotes hair follicle growth in mice by enhancing IGF-1 expression in dermal papilla cells.

This study found that cow placenta extract increased hair follicle size and hair length in mice but was less effective than minoxidil, suggesting potential with further refinement.

This review explores the potential impact of hormonal changes during aging on benign prostate hyperplasia-related urinary symptoms and metabolic syndrome, highlighting the hypothesis of a male PCOS-equivalent but reports no new clinical results.

This study found that maternal Nano-Se supplementation in cashmere goats improved antioxidant status and promoted secondary hair follicle development in fetuses at 110 days.

This study found that micro-current electrical stimulation may promote hair growth in human hair follicle-derived papilla cells and a mice model by enhancing cell proliferation, migration, and activating key growth pathways.

This study found that overexpressing the 14-3-3σ protein in transgenic mice reduced keratinocyte proliferation and migration, leading to thinner epidermis and fewer hair follicles due to IGF-1 pathway inhibition.

This study observed that certain herbal extracts may promote hair growth and inhibit hair loss in cell lines by affecting specific protein expressions similarly to minoxidil.

This study discusses how redox imbalance, specifically through reduced Insulin-like Growth Factor-1 mediated by the transcription factor JunB and sphingolipid metabolism changes, contributes to skin aging by depleting stem cell pools and altering the extracellular matrix, ultimately impacting skin integrity and function.

This review highlights surprising similarities between hair follicles and antler units, suggesting that a comparative study of their biology could benefit understanding in both areas without presenting new empirical findings.

This review explores the potential link between psoriasis and metabolic syndrome, focusing on how disturbances in growth factors may connect these conditions and contribute to symptoms like keratinocyte proliferation and inflammation.

This study suggests that hair follicle mesenchymal stem cells may alleviate small intestinal ischemia-reperfusion injury in rats by promoting angiogenesis, reducing apoptosis, and enhancing intestinal stem cell expression.

This study found that methionine supplementation improved hair follicle density in heat-stressed Rex rabbits, likely through various signaling pathways, despite an increase in stress indicators.

This study suggests that CGE may enhance hair growth by activating β-catenin signaling pathways in human hair dermal papilla cells and promoting the anagen growth phase in mice.

This study found that intramuscular injections of a PRP-derivative in healthy beagle dogs did not result in statistically significant changes in lumbar muscle tissue or IGF-1 blood concentration, suggesting the treatment may be safe at therapeutic doses.

This study demonstrated that water-soluble peptides from egg yolk, termed "hair growth peptide," stimulated human hair follicle cell growth and improved hair growth in female pattern hair loss.

In this study, Rosa multiflora root extracts showed strong antioxidant activity and promoted expression of growth factors IGF1 and PDGFB, suggesting potential use as a natural hair growth agent.