Dietary Vitamin D Supplementation Improves Hair Follicle Development and Affects Fatty Acid Metabolism in Rex Rabbits

    July 2025 in “ Food Science & Nutrition ”
    Xiang Li, Xiaojing Wu, Fuchang Li, Lei Liu
    Studysummary This study found that vitamin D supplementation in diets of Rex rabbits improved hair follicle development and fatty acid metabolism, with 1400–2100 IU/kg proving most effective for hair density and 2800 IU/kg increasing hair length.
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    Research cited in this study 18

    1. MicroRNA-205 Promotes Hair Regeneration by Modulating Mechanical Properties of Hair Follicle Stem Cells Proceedings of the National Academy of Sciences · 2023
    2. Morphogenesis, Growth Cycle, and Molecular Regulation of Hair Follicles Frontiers in Cell and Developmental Biology · 2022
    3. Vitamin A Alleviates Heat Stress-Induced Damage to Hair Follicle Development in Rex Rabbits Journal of the Science of Food and Agriculture · 2021
    4. Pyridoxine Regulates Hair Follicle Development via the PI3K/Akt, Wnt, and Notch Signalling Pathways in Rex Rabbits Animal nutrition · 2021
    5. Efficacy of Oral Vitamin D3 Therapy in Patients Suffering from Diffuse Hair Loss (Telogen Effluvium) Journal of Nutritional Science and Vitaminology · 2021
    6. Hedgehog Stimulates Hair Follicle Neogenesis by Creating Inductive Dermis During Murine Skin Wound Healing Nature Communications · 2018
    7. Symptomatic Hypercalcemia and Scarring Alopecia as Presenting Features of Sarcoidosis Proceedings - Baylor University. Medical Center · 2018
    8. Diet and Hair Loss: Effects of Nutrient Deficiency and Supplement Use Dermatology practical & conceptual · 2017
    9. Serum Vitamin D3 Levels and Diffuse Hair Fall Among the Student Population in South India: A Case-Control Study International journal of trichology · 2016
    10. Serum Vitamin D3 Level in Patients with Female Pattern Hair Loss International Journal of Trichology · 2016
    11. Signaling Involved in Hair Follicle Morphogenesis and Development International Journal of Molecular Sciences · 2014
    12. Reciprocal Role of Vitamin D Receptor on β-Catenin Regulated Keratinocyte Proliferation and Differentiation The Journal of Steroid Biochemistry and Molecular Biology · 2013
    13. Shh Maintains Dermal Papilla Identity and Hair Morphogenesis via a Noggin–Shh Regulatory Loop Genes & Development · 2012
    14. The Hair Cycle and Vitamin D Receptor Archives of Biochemistry and Biophysics · 2011
    15. KGF And EGF Signaling Block Hair Follicle Induction And Promote Interfollicular Epidermal Fate In Developing Mouse Skin Development · 2009
    16. The Preventive Effect of Vitamin D3 on Radiation-Induced Hair Toxicity in a Rat Model Life sciences · 2005
    17. Bone Morphogenetic Proteins and Their Antagonists in Skin and Hair Follicle Biology Journal of Investigative Dermatology · 2003
    18. Overexpression of Insulin-Like Growth Factor-1 Induces Hyperplasia, Dermal Abnormalities, and Spontaneous Tumor Formation in Transgenic Mice Oncogene · 1997

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