TLDR Transplanted hair follicle stem cells can heal damaged rat intestines.
The study demonstrates that transplanted hair follicle mesenchymal stem cells (HFMSCs) can effectively treat small intestinal ischemia-reperfusion (IR) injury in rats. HFMSCs home to the damaged site, proliferate, and differentiate into intestinal stem cells, promoting tissue repair and regeneration. They enhance angiogenesis, reduce apoptosis, and mitigate oxidative stress, thereby improving intestinal morphology and function. The findings suggest HFMSCs as a promising therapeutic approach for intestinal IR injury through intrinsic and paracrine mechanisms.
8 citations
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February 2021 in “Journal of Clinical Medicine” Hair follicle stem cells are promising for blood vessel formation and tissue repair.
8 citations
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January 2021 in “PubMed” Hair follicle stem cells may help treat acute pancreatitis by reducing inflammation and aiding regeneration.
3 citations
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January 2021 in “Oxidative Medicine and Cellular Longevity” Nrf-2-modified stem cells from hair follicles significantly improve ulcerative colitis in rats.
263 citations
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February 2020 in “International journal of molecular sciences” ADSCs help in wound healing and skin regeneration but need more research for full understanding.
64 citations
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December 2012 in “Stem Cell Reviews and Reports” 
73 citations
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August 2011 in “Stem Cell Research” Human hair follicle stem cells can turn into multiple cell types but lose some of this ability after being grown in the lab for a long time.
88 citations
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January 2019 in “Journal of Tissue Engineering and Regenerative Medicine” Conditioned media from mesenchymal stem cell cultures could be a more effective alternative for regenerative therapies, but more research is needed.
