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research Transplanted Hair Follicle Mesenchymal Stem Cells Alleviated Small Intestinal Ischemia–Reperfusion Injury via Intrinsic and Paracrine Mechanisms in a Rat Model

6 citations, October 2022 in “Frontiers in Cell and Developmental Biology”

Hair follicle mesenchymal stem cells (HFMSCs) were found to alleviate small intestinal ischemia-reperfusion (IR) injury in a rat model by homing to damaged sites, differentiating into intestinal stem cells (ISCs), and promoting angiogenesis through increased levels of ANG1, VEGF, and IGF1. HFMSCs also reduced apoptosis by modulating Bcl-2 and Bax expression, decreased oxidative stress by lowering MDA and increasing SOD levels, and protected the intestinal mucosal barrier as indicated by elevated DAO levels. These findings suggest HFMSCs as a promising treatment for small intestinal IR injury.

research From Hair to Colon: Hair Follicle-Derived MSCs Alleviate Pyroptosis in DSS-Induced Ulcerative Colitis by Releasing Exosomes in a Paracrine Manner

1 citations, September 2022 in “Oxidative Medicine and Cellular Longevity”

Hair follicle stem cells can help treat ulcerative colitis in mice by releasing beneficial exosomes.

research Hair Follicle Mesenchymal Stem Cell Exosomal LncRNA H19 Inhibited NLRP3 Pyroptosis to Promote Diabetic Mouse Skin Wound Healing

13 citations, February 2023 in “Aging”

A substance from hair follicle stem cells helps heal skin wounds in diabetic mice by promoting cell growth and preventing cell death.

research The Potential of a Hair Follicle Mesenchymal Stem Cell-Conditioned Medium for Wound Healing and Hair Follicle Regeneration

6 citations, April 2020 in “Applied sciences”

Hair growth medium helps heal wounds and regrow hair in mice.

research Water Extract of Cacumen Platycladi Promotes Hair Growth Through the Akt/GSK3β/β-Catenin Signaling Pathway

February 2023 in “Frontiers in Pharmacology”

Water extract of Cacumen Platycladi helps hair growth by activating specific cell pathways.

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community TDM-105795 phase 2 results are in!

in Research/Science 28 upvotes 7 months ago

TDM-105795 showed promising hair growth results, with higher efficacy than placebo and minimal side effects. It activates dormant hair follicle stem cells and may maintain gains without immediate loss, unlike minoxidil.

community New and Interesting HairLoss Studies/Papers/Reviews

in Treatment 41 upvotes 4 years ago

Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.