Administration of Nrf-2-Modified Hair-Follicle MSCs Ameliorates DSS-Induced Ulcerative Colitis in Rats
January 2021
in “
Oxidative Medicine and Cellular Longevity
”
Nrf-2 hair-follicle mesenchymal stem cells HF-MSCs dextran sulfate sodium ulcerative colitis intestinal stem cell inflammatory factors anti-inflammatory factors disease activity index hair-follicle stem cells DSS UC intestinal stem cells inflammatory markers anti-inflammatory markers disease activity
Studysummary In this study, Nrf-2-expressing hair follicle mesenchymal stem cells showed the most significant therapeutic effect in a rat model of ulcerative colitis, suggesting a new potential treatment for the disease.
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