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GlossaryUlcerative Colitis (UC)

chronic inflammatory bowel disease affecting the colon and rectum

Ulcerative Colitis (UC) is a chronic inflammatory bowel disease (IBD) that primarily affects the colon and rectum, causing inflammation and ulcers in the lining of the large intestine. Symptoms often include abdominal pain, diarrhea mixed with blood, and an urgent need to defecate. The exact cause is unknown, but it is believed to involve an abnormal immune response, genetic factors, and environmental triggers.

Related Terms

Learn

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learn PP405

mitochondrial pyruvate carrier (MPC) inhibitor by Pelage in early trials

learn Hair Multiplication

extract, clone, and reinsert your own hair cells

Research

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research Clinical Insights for Hair Restoration: A Case Study on UC-MSCs Derived Secretome Therapy in Alopecia

April 2025 in “Cytotherapy”

UC-MSCs derived secretome therapy may help treat hair loss safely.

research Exploring the Role of UC-MSC-Derived Exosomes in Boosting HHDPCs Proliferation for Hair Growth via AKT Activation

January 2024

UC-MSC-derived exosomes may help treat hair loss by promoting hair cell growth through AKT activation.

research Effects And Uses Of Caffeine In Cosmetics

January 2020

Caffeine in cosmetics has antioxidant effects, protects against UV, reduces cellulite, and stimulates hair growth.

research LGBTQ+ STEM at UCL Network: Fostering an Inclusive and Visible Community

September 2021 in “Physiology News”

The LGBTQ+ STEM @UCL Network helps increase visibility and support for LGBTQ+ individuals in STEM at University College London.

Observational Real-World Evidence on the Efficacy and Safety of Janus Kinase Inhibitors in the Treatment of Moderate to Severe Active Ulcerative Colitis

research Observational Real-World Evidence on the Efficacy and Safety of Janus Kinase Inhibitors in the Treatment of Moderate to Severe Active Ulcerative Colitis

January 2024 in “Journal of Crohn's and colitis”

Janus Kinase inhibitors are effective and have an acceptable safety profile for treating moderate to severe Ulcerative Colitis.

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Community Join

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community UCLA scientists found a molecule — PP405 — that wakes up sleeping hair follicles and tells them, “Do your job.”

in Research/Science 1332 upvotes 3 weeks ago

PP405 is a promising molecule that may reactivate dormant hair follicles, potentially offering a new treatment for hair loss. It is in phase 2 trials, with possible availability between 2027 and 2030.

community Did Scientists Just Cure Baldness? UCLA’s New Molecule Could Revolutionize Hair Growth

in Treatment 561 upvotes 2 months ago

PP405 shows promise for hair growth but may need continuous use like Minoxidil. Current treatments include Minoxidil, finasteride, and dutasteride, with skepticism about a true cure due to financial interests.

community SCUBE3 video, link below. Nothing new but it’s something to watch

in Research/Science 7 upvotes 2 years ago

Hair loss discussion includes treatments Minoxidil, Finasteride, and RU58841. UC Irvine scientists discover possible baldness cure.

community Progress over one year. June 2022 > June 2023 (fin+min)

in Progress Pictures 685 upvotes 1 year ago

A user's one-year progress in hair loss treatment using finasteride and minoxidil. The user shared their experience and advice, including adjusting the amount of sprays used based on individual needs and the importance of patience and positivity in the process.

community Fin 3xweek and dermarolling since end of April – October

in Progress Pictures 124 upvotes 2 years ago

A user's progress with finasteride and dermarolling to regrow their hairline, with other users noting the improvement.

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