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    GlossaryUlcerative Colitis (UC)

    chronic inflammatory bowel disease affecting the colon and rectum

    Ulcerative Colitis (UC) is a chronic inflammatory bowel disease (IBD) that primarily affects the colon and rectum, causing inflammation and ulcers in the lining of the large intestine. Symptoms often include abdominal pain, diarrhea mixed with blood, and an urgent need to defecate. The exact cause is unknown, but it is believed to involve an abnormal immune response, genetic factors, and environmental triggers.

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      mitochondrial pyruvate carrier (MPC) inhibitor by Pelage in early trials

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