April 2025 in “OPAL (Open@LaTrobe) (La Trobe University)” This study found that exosomes derived from human umbilical cord mesenchymal stem cells enhanced the growth of human hair dermal papilla cells by promoting cell cycle progression and activating PI3K and Akt-dependent pathways, indicating potential for hair loss treatment.
In this study, human hair dermal papilla cells were incubated with varying concentrations of umbilical cord-derived mesenchymal stem cell exosomes or minoxidil, and cell proliferation was assessed, showing significant results compared to the control.
This study found that exosomes derived from human umbilical cord mesenchymal stem cells effectively promoted growth in human hair dermal papilla cells, implicating the PI3K and Akt pathways as potential targets for treating hair loss.
July 2024 in “Acta Histochemica” This study investigates the potential of umbilical cord mesenchymal stem cells exosome (UCMSC-Exos) to promote hair growth, focusing on its mechanisms of action, though specific results are not reported.
June 2026 in “Journal of Nanobiotechnology” This study reported that human umbilical cord mesenchymal stem cell-derived exosomes may promote hair regeneration and thickness in androgenic alopecia by modulating cellular pathways in hair growth, including increasing hair density and diameter, as observed in a mouse model and an exploratory clinical trial.
